Innate immune receptors recognize microorganism-specific motifs. One such receptor–
ligand complex is formed between the mammalian Toll-like receptor 4 (TLR4)–MD2–CD14 …

Since first being described in the fruit fly Drosophila melanogaster, Toll-like receptors (TLRs)
have proven to be of great interest to immunologists and investigators interested in the …

Toll-like receptors (TLRs) play an important part in the innate immune recognition of
invading microorganisms, initiating sufficient immune responses. Growing amounts of data …

Lipopolysaccharide is an essential macromolecule that comprises the outer surface of
gramnegative bacteria. Lipopolysaccharide, recognized by the human host as a foreign …

В последнее время накапливается все больше данных, свидетельствующих о том, что
полиморфизм единичных нуклеотидов (SNP) за счет формирования специфических …

In addition to its well-known role in mineral and skeletal homeostasis, 1, 25-
dihydroxyvitamin D3 [1, 25-(OH) 2, D3] regulates the differentiation, growth and function of a …

Toll like receptors (TLRs) are a class of pattern recognition receptors belonging to the innate
immune system. Mutations in the protein coding region of TLRs are associated with altered …

Endotoxin (lipopolysaccharides; LPS) plays a pivotal role in many pathophysiological states
and diseases. Although the major pathways involved in LPS signal transduction are …

Toll-like receptors (TLRs) recognize various microbial components and induce immune
responses. Polymorphisms in TLRs may influence their recognition of pathogen-derived …

Toll-like receptors (TLRs), a large group of proteins which recognize various pathogen-
associated molecular patterns, are critical for the normal function of the innate immune …