NANOBODY®(a registered trademark of Ablynx NV) molecules (Nbs), also referred to as
single domain-based VHHs, are antibody fragments derived from heavy-chain only IgG …

Biologics have become an important area of medical research generating therapeutics
essential for the treatment of many disease states. Biologics are defined as biologically …

Clostridioides difficile (C. difficile), known as the major cause of antibiotic-associated
diarrhea, is regarded as one of the most common healthcare-associated bacterial infections …

The rapid expansion of the application of pharmaceutical proteins and industrial enzymes
requires robust microbial workhorses for high protein production. The budding yeast …

Traditionally, recombinant protein production has been done in several expression hosts of
bacteria, fungi, and majorly CHO (Chinese Hamster Ovary) cells; few have high production …

The advancement of genetic engineering has revolutionized the field of immunology by
allowing the utilization of intrinsic antibody structures. One of the biologics that are being …

The field of cancer treatment has evolved significantly over the last decade with the
emergence of next-generation therapeutic antibodies. Conventional treatments like …

Antibodies have highly attracted in treating various diseases such as cancer and viral
infections over traditional chemical treatments to improve efficiency. However, their large …

Antibody fragments and their engineered variants show true potential as next-generation
therapeutics as they combine excellent targeting with superior biodistribution and blood …

High-level production of recombinant proteins in industrial microorganisms is often limited
by the formation of misfolded proteins or protein aggregates, which consequently induce …