Considerable progress has been made in recent years in the structural and molecular
biology of type IV secretion systems in Gram-negative bacteria. The latest advances have …

Colonization of the human stomach with Helicobacter pylori strains containing the cag
pathogenicity island is a risk factor for development of gastric cancer. The cag pathogenicity …

Inspired by the natural pathogen–host interactions and adhesion, this study reports on the
development of a novel targeted nanotherapeutic for the treatment of Helicobacter pylori …

In this review, we highlight progress in the last year in characterizing known virulence factors
like flagella and the Cag type IV secretion system with sophisticated structural and …

The pathogenic bacterium Helicobacter pylori is genetically highly diverse and a major risk
factor for the development of peptic ulcer disease and gastric adenocarcinoma in humans …

Helicobacter pylori infection is one of the leading causes of several gastroduodenal
diseases, such as gastritis, peptic ulcer, and gastric cancer. In fact, H. pylori eradication …

Translocation of the Helicobacter pylori (Hp) cytotoxin-associated gene A (CagA) effector
protein via the cag-Type IV Secretion System (cag-T4SS) into host cells is a hallmark of …

Helicobacter pylori (Hp) is an important human pathogen associated with gastric
inflammation and neoplasia. It is commonly believed that this bacterium avoids major …

The human gastric pathogen Helicobacter pylori activates human epithelial cells by a
particular combination of mechanisms, including NOD1 and ALPK1-TIFA activation. These …

Helicobacter pylori chronically infects nearly half the world's population, yet most of those
infected remain asymptomatic throughout their lifetime. The outcome of infection—peptic …