Genetics and epigenetics of eating disorders

Z Yilmaz, JA Hardaway, CM Bulik - Advances in genomics and …, 2015 - Taylor & Francis
Eating disorders (EDs) are serious psychiatric conditions influenced by biological,
psychological, and sociocultural factors. A better understanding of the genetics of these …

Dysfunctions of leptin, ghrelin, BDNF and endocannabinoids in eating disorders: beyond the homeostatic control of food intake

P Monteleone, M Maj - Psychoneuroendocrinology, 2013 - Elsevier
A large body of literature documents the occurrence of alterations in the physiology of both
central and peripheral modulators of appetite in acute patients with anorexia nervosa (AN) …

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11. 2 locus

S Jacquemont, A Reymond, F Zufferey, L Harewood… - Nature, 2011 - nature.com
Both obesity and being underweight have been associated with increased mortality,.
Underweight, defined as a body mass index (BMI)≤ 18.5 kg per m2 in adults and≤− 2 …

A genetic basis for functional hypothalamic amenorrhea

LM Caronia, C Martin, CK Welt… - … England Journal of …, 2011 - Mass Medical Soc
Background Functional hypothalamic amenorrhea is a reversible form of gonadotropin-
releasing hormone (GnRH) deficiency commonly triggered by stressors such as excessive …

Gene environment interaction studies in depression and suicidal behavior: an update

L Mandelli, A Serretti - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Increasing evidence supports the involvement of both heritable and environmental risk
factors in major depression (MD) and suicidal behavior (SB). Studies investigating gene …

The impact of non-additive genetic associations on age-related complex diseases

M Guindo-Martínez, R Amela, S Bonàs-Guarch… - Nature …, 2021 - nature.com
Genome-wide association studies (GWAS) are not fully comprehensive, as current strategies
typically test only the additive model, exclude the X chromosome, and use only one …

Brain-derived neurotrophic factor, food intake regulation, and obesity

H Rosas-Vargas, JD Martínez-Ezquerro… - Archives of medical …, 2011 - Elsevier
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a fundamental role in
development and plasticity of the central nervous system (CNS). It is currently recognized as …

Obesity susceptibility loci and uncontrolled eating, emotional eating and cognitive restraint behaviors in men and women

MC Cornelis, EB Rimm, GC Curhan, P Kraft… - …, 2014 - Wiley Online Library
Objective Many confirmed genetic loci for obesity are expressed in regions of the brain that
regulate energy intake and reward‐seeking behavior. Whether these loci contribute to the …

Eating disorders, gene–environment interactions and epigenetics

IC Campbell, J Mill, R Uher, U Schmidt - Neuroscience & Biobehavioral …, 2011 - Elsevier
This review describes the various subtypes of eating disorders and examines factors
associated with the risk of illness. It considers evidence that the development and …

Los trastornos de la conducta alimentaria

JP Méndez, V Vázquez-Velazquez… - Boletín Médico del …, 2008 - scielo.org.mx
Los trastornos de la conducta alimentaria constituyen alteraciones severas en la ingesta de
los alimentos, en personas que presentan patrones distorsionados en el acto de comer en …