Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023 - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Young-onset colorectal cancer

MCW Spaander, AG Zauber, S Syngal… - Nature reviews Disease …, 2023 - nature.com
In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …

Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …

Fusobacterium nucleatum, a key pathogenic factor and microbial biomarker for colorectal cancer

N Wang, JY Fang - Trends in Microbiology, 2023 - cell.com
Colorectal cancer (CRC), one of the most prevalent cancers, has complex etiology. The
dysbiosis of intestinal bacteria has been highlighted as an important contributor to CRC …

A review of cancer immunotherapy: from the past, to the present, to the future

K Esfahani, L Roudaia, N Buhlaiga, SV Del Rincon… - Current …, 2020 - mdpi.com
A review of cancer immunotherapy: from the past, to the present, to the future Page 1 S87
Current Oncology, Vol. 27, Supp. 2, April 2020 © 2020 Multimed Inc. REVIEW ARTICLE A …

An umbrella review of the evidence linking oral health and systemic noncommunicable diseases

J Botelho, P Mascarenhas, J Viana, L Proença… - Nature …, 2022 - nature.com
Oral diseases are highly prevalent worldwide. Recent studies have been supporting a
potential bidirectional association of oral diseases with systemic noncommunicable …

The role of oral bacteria in inflammatory bowel disease

E Read, MA Curtis, JF Neves - Nature Reviews Gastroenterology & …, 2021 - nature.com
Over the past two decades, the importance of the microbiota in health and disease has
become evident. Pathological changes to the oral bacterial microbiota, such as those …

The oral microbiome and cancer

M Irfan, RZR Delgado, J Frias-Lopez - Frontiers in immunology, 2020 - frontiersin.org
There is mounting evidence that members of the human microbiome are highly associated
with a wide variety of cancer types. Among oral cancers, oral squamous cell carcinoma …

Clostridium butyricum, a butyrate-producing probiotic, inhibits intestinal tumor development through modulating Wnt signaling and gut microbiota

D Chen, D Jin, S Huang, J Wu, M Xu, T Liu, W Dong… - Cancer letters, 2020 - Elsevier
Gut microbiota dysbiosis is closely involved in intestinal carcinogenesis. A marked reduction
in butyrate-producing bacteria has been observed in patients with colorectal cancer (CRC); …

The microbiome and gynaecological cancer development, prevention and therapy

P Łaniewski, ZE Ilhan, MM Herbst-Kralovetz - Nature Reviews Urology, 2020 - nature.com
The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …