Clinical review: intensive care unit acquired weakness
G Hermans, G Van den Berghe - Critical care, 2015 - Springer
A substantial number of patients admitted to the ICU because of an acute illness,
complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle …
complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle …
Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects
FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …
provides a comprehensive and up-to-date account on the latest developments in the area of …
[HTML][HTML] Critical illness polyneuropathy, myopathy and neuronal biomarkers in COVID-19 patients: A prospective study
R Frithiof, E Rostami, E Kumlien, J Virhammar… - Clinical …, 2021 - Elsevier
Objective The aim was to characterize the electrophysiological features and plasma
biomarkers of critical illness polyneuropathy (CIN) and myopathy (CIM) in coronavirus …
biomarkers of critical illness polyneuropathy (CIN) and myopathy (CIM) in coronavirus …
Neurofilament light chains to assess sepsis-associated encephalopathy: Are we on the track toward clinical implementation?
B Bircak-Kuchtova, HY Chung, J Wickel, J Ehler… - Critical Care, 2023 - Springer
Sepsis is the most common cause of admission to intensive care units worldwide. Sepsis
patients frequently suffer from sepsis-associated encephalopathy (SAE) reflecting acute …
patients frequently suffer from sepsis-associated encephalopathy (SAE) reflecting acute …
[HTML][HTML] Fluid biomarkers for monitoring structural changes in polyneuropathies: their use in clinical practice and trials
L Wieske, D Smyth, MP Lunn, F Eftimov, CE Teunissen - Neurotherapeutics, 2021 - Elsevier
Reliable and responsive tools for monitoring disease activity and treatment outcomes in
patients with neuropathies are lacking. With the emergence of ultrasensitive blood …
patients with neuropathies are lacking. With the emergence of ultrasensitive blood …
Neurofilament light increases over time in severe COVID-19 and is associated with delirium
PJ Smeele, L Vermunt, S Blok, JW Duitman… - Brain …, 2022 - academic.oup.com
Neurological monitoring in sedated Intensive Care Unit patients is constrained by the lack of
reliable blood-based biomarkers. Neurofilament light is a cross-disease biomarker for …
reliable blood-based biomarkers. Neurofilament light is a cross-disease biomarker for …
Neuro-axonal injury in COVID-19: the role of systemic inflammation and SARS-CoV-2 specific immune response
C Hirzel, D Grandgirard, B Surial… - Therapeutic …, 2022 - journals.sagepub.com
Background: In coronavirus disease-2019 (COVID-19) patients, there is increasing evidence
of neuronal injury by the means of elevated serum neurofilament light chain (sNfL) levels …
of neuronal injury by the means of elevated serum neurofilament light chain (sNfL) levels …
A conceptual framework: the early and late phases of skeletal muscle dysfunction in the acute respiratory distress syndrome
Patients with acute respiratory distress syndrome (ARDS) often develop severe
diaphragmatic and limb skeletal muscle dysfunction. Impaired muscle function in ARDS is …
diaphragmatic and limb skeletal muscle dysfunction. Impaired muscle function in ARDS is …
Urinary titin is a novel biomarker for muscle atrophy in nonsurgical critically ill patients: a two-center, prospective observational study
N Nakanishi, R Tsutsumi, K Hara… - Critical Care …, 2020 - journals.lww.com
Objectives: Although skeletal muscle atrophy is common in critically ill patients, biomarkers
associated with muscle atrophy have not been identified reliably. Titin is a spring-like protein …
associated with muscle atrophy have not been identified reliably. Titin is a spring-like protein …
Intensive care unit-acquired weakness
J Horn, G Hermans - Handbook of Clinical Neurology, 2017 - Elsevier
When critically ill, a severe weakness of the limbs and respiratory muscles often develops
with a prolonged stay in the intensive care unit (ICU), a condition vaguely termed intensive …
with a prolonged stay in the intensive care unit (ICU), a condition vaguely termed intensive …