Recent progress in biological activities of synthesized phenothiazines
K Pluta, B Morak-Młodawska, M Jeleń - European journal of medicinal …, 2011 - Elsevier
This review summarizes recent medicinal chemistry investigations in vitro and in vivo in
search for new phenothiazines of promising biological activities. New phenothiazine …
search for new phenothiazines of promising biological activities. New phenothiazine …
Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration
Iron dysregulation has been implicated in multiple neurodegenerative diseases, including
Parkinson's disease (PD). Iron-loaded microglia are frequently found in affected brain …
Parkinson's disease (PD). Iron-loaded microglia are frequently found in affected brain …
Macrophages: an elusive yet emerging therapeutic target of atherosclerosis
Macrophages are central to the initiation and progression of atherosclerosis and thus can be
very appropriate targets for therapy. Cell adhesion molecules mediating monocytes …
very appropriate targets for therapy. Cell adhesion molecules mediating monocytes …
Molecular iodine promoted synthesis of new pyrazolo [3, 4-d] pyrimidine derivatives as potential antibacterial agents
M Bakavoli, G Bagherzadeh, M Vaseghifar… - European journal of …, 2010 - Elsevier
Molecular iodine promoted synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as potential
antibacterial agents - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals …
antibacterial agents - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals …
Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors …
Emerging evidence points to the intertwining framework of inflammation and oxidative stress
in various ailments. We speculate on the potential impact of the magic shotgun approach in …
in various ailments. We speculate on the potential impact of the magic shotgun approach in …
[HTML][HTML] A review: Medicinally important nitrogen sulphur containing heterocycles
Nitrogen sulphur containing heterocycles have specific properties due to which they can be
used as a potential material in a different type of industries such as medicinal …
used as a potential material in a different type of industries such as medicinal …
15-Lipoxygenase inhibitors: a patent review
H Sadeghian, A Jabbari - Expert opinion on therapeutic patents, 2016 - Taylor & Francis
Introduction: 15-Lipoxygenases (15-LOXes) are a family of iron-containing proteins that
have the capability for unsaturated fatty acid peroxidation in animals and plants. Two types …
have the capability for unsaturated fatty acid peroxidation in animals and plants. Two types …
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1
There are a variety of lipoxygenases in the human body (hLO), each having a distinct role in
cellular biology. Human reticulocyte 15-lipoxygenase-1 (15-hLO-1), which catalyzes the …
cellular biology. Human reticulocyte 15-lipoxygenase-1 (15-hLO-1), which catalyzes the …
The importance of 15-lipoxygenase inhibitors in cancer treatment
Cancer-targeted therapy is an expanding and successful approach in treatment of many
types of cancers. One of the main categories of targeted therapy is use of small molecule …
types of cancers. One of the main categories of targeted therapy is use of small molecule …
Azaphenothiazines–promising phenothiazine derivatives. An insight into nomenclature, synthesis, structure elucidation and biological properties
K Pluta, M Jeleń, B Morak-Młodawska… - European Journal of …, 2017 - Elsevier
For the last two decades, classical phenothiazines have attracted attention of researchers,
as the hitherto investigations have revealed many significant biological activities within this …
as the hitherto investigations have revealed many significant biological activities within this …