Biological small-angle neutron scattering: recent results and development

E Mahieu, F Gabel - Acta Crystallographica Section D: Structural …, 2018 - journals.iucr.org
Small-angle neutron scattering (SANS) has increasingly been used by the structural biology
community in recent years to obtain low-resolution information on solubilized …

Halogenation as a tool to tune antimicrobial activity of peptoids

N Molchanova, JE Nielsen, KB Sørensen… - Scientific reports, 2020 - nature.com
Antimicrobial peptides have attracted considerable interest as potential new class of
antibiotics against multi-drug resistant bacteria. However, their therapeutic potential is …

[HTML][HTML] Breaking free from the crystal lattice: Structural biology in solution to study protein degraders

K Haubrich, VA Spiteri, W Farnaby, F Sobott… - Current Opinion in …, 2023 - Elsevier
Structural biology offers a versatile arsenal of techniques and methods to investigate the
structure and conformational dynamics of proteins and their assemblies. The growing field of …

[PDF][PDF] BioSAXS Sample Changer: a robotic sample changer for rapid and reliable high-throughput X-ray solution scattering experiments

A Round, F Felisaz, L Fodinger, A Gobbo… - … Section D: Biological …, 2015 - journals.iucr.org
Small-angle X-ray scattering (SAXS) of macromolecules in solution is in increasing demand
by an ever more diverse research community, both academic and industrial. To better serve …

Beamline B21: high-throughput small-angle X-ray scattering at Diamond Light Source

NP Cowieson, CJC Edwards-Gayle, K Inoue… - Synchrotron …, 2020 - journals.iucr.org
B21 is a small-angle X-ray scattering (SAXS) beamline with a bending magnet source in the
3 GeV storage ring at the Diamond Light Source Ltd synchrotron in the UK. The beamline …

Stability of nanopeptides: structure and molecular exchange of self-assembled peptide fibers

N König, SM Szostak, JE Nielsen, M Dunbar… - ACS …, 2023 - ACS Publications
Often nanostructures formed by self-assembly of small molecules based on hydrophobic
interactions are rather unstable, causing morphological changes or even dissolution when …

Influenza polymerase can adopt an alternative configuration involving a radical repacking of PB2 domains

E Thierry, D Guilligay, J Kosinski, T Bock, S Gaudon… - Molecular cell, 2016 - cell.com
Influenza virus polymerase transcribes or replicates the segmented RNA genome (vRNA)
into respectively viral mRNA or full-length copies and initiates RNA synthesis by binding the …

Shared metadata for data-centric materials science

LM Ghiringhelli, C Baldauf, T Bereau, S Brockhauser… - Scientific Data, 2023 - nature.com
The expansive production of data in materials science, their widespread sharing and
repurposing requires educated support and stewardship. In order to ensure that this need …

[PDF][PDF] BioSAXS at European Synchrotron Radiation Facility–Extremely Brilliant Source: BM29 with an upgraded source, detector, robot, sample environment, data …

MD Tully, J Kieffer, ME Brennich… - Journal of …, 2023 - journals.iucr.org
As part of its Extremely Brilliant Source (EBS) upgrade project, the ESRF's BM29 BioSAXS
beamline was subject to a significant upgrade and refurbishment. In addition to the …

Online data analysis at the ESRF bioSAXS beamline, BM29

ME Brennich, J Kieffer, G Bonamis… - Journal of Applied …, 2016 - journals.iucr.org
High-throughput small-angle X-ray scattering on proteins in solution (bioSAXS) at
synchrotron sources is a commonly used technique in structural biology, which relies on …