Neocortical layer 1: an elegant solution to top-down and bottom-up integration
B Schuman, S Dellal, A Prönneke… - Annual review of …, 2021 - annualreviews.org
Many of our daily activities, such as riding a bike to work or reading a book in a noisy cafe,
and highly skilled activities, such as a professional playing a tennis match or a violin …
and highly skilled activities, such as a professional playing a tennis match or a violin …
Connectomic comparison of mouse and human cortex
The human cerebral cortex houses 1000 times more neurons than that of the cerebral cortex
of a mouse, but the possible differences in synaptic circuits between these species are still …
of a mouse, but the possible differences in synaptic circuits between these species are still …
[HTML][HTML] Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity
We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …
A dendrite-focused framework for understanding the actions of ketamine and psychedelics
NK Savalia, LX Shao, AC Kwan - Trends in neurosciences, 2021 - cell.com
Pilot studies have hinted that serotonergic psychedelics such as psilocybin may relieve
depression, and could possibly do so by promoting neural plasticity. Intriguingly, another …
depression, and could possibly do so by promoting neural plasticity. Intriguingly, another …
Connectomes across development reveal principles of brain maturation
An animal's nervous system changes as its body grows from birth to adulthood and its
behaviours mature,,,,,,–. The form and extent of circuit remodelling across the connectome is …
behaviours mature,,,,,,–. The form and extent of circuit remodelling across the connectome is …
[HTML][HTML] Neuropathic pain caused by miswiring and abnormal end organ targeting
V Gangadharan, H Zheng, FJ Taberner, J Landry… - Nature, 2022 - nature.com
Nerve injury leads to chronic pain and exaggerated sensitivity to gentle touch (allodynia) as
well as a loss of sensation in the areas in which injured and non-injured nerves come …
well as a loss of sensation in the areas in which injured and non-injured nerves come …
Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain
A Bhattacherjee, C Zhang, BR Watson… - Nature …, 2023 - nature.com
The prefrontal cortex (PFC) is a complex brain region that regulates diverse functions
ranging from cognition, emotion and executive action to even pain processing. To decode …
ranging from cognition, emotion and executive action to even pain processing. To decode …
Structure and function of axo-axonic inhibition
CM Schneider-Mizell, AL Bodor, F Collman, D Brittain… - Elife, 2021 - elifesciences.org
Inhibitory neurons in mammalian cortex exhibit diverse physiological, morphological,
molecular, and connectivity signatures. While considerable work has measured the average …
molecular, and connectivity signatures. While considerable work has measured the average …
Dense neuronal reconstruction through X-ray holographic nano-tomography
AT Kuan - Biophysical Journal, 2020 - cell.com
1416-Pos Modulation of Human Stem Cell Derived Neuron Activity through Addition of an
External Conductance using Dynamic Clamp Brian K. Panama1, Leigh Korbel1, Brandon …
External Conductance using Dynamic Clamp Brian K. Panama1, Leigh Korbel1, Brandon …
Postnatal connectomic development of inhibition in mouse barrel cortex
INTRODUCTION The establishment of neuronal circuits in the cerebral cortex of mammals is
an important developmental process extending over embryonic and postnatal periods, from …
an important developmental process extending over embryonic and postnatal periods, from …