The extracellular regulated kinase/microtubule-associated protein kinase (ERK/MAPK)
signalling pathway transduces signals that cause an alteration in the ongoing metabolic …

Methyl-CpG-binding protein 2 (MeCP2) is a transcriptional regulator that is highly abundant
in the brain. It binds to methylated genomic DNA to regulate a range of physiological …

Rett syndrome (RTT) is a neurodevelopmental disorder caused predominantly by loss-of-
function mutations in the gene Methyl-CpG-binding protein 2 (MECP2), which encodes the …

The way in which brain morphology and proteome are remodeled during embryonal
development, and how they are linked to the cellular metabolism, could be a key for …

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with increasing
prevalence. Over 1,000 risk genes have now been implicated in ASD, suggesting diverse …

Methyl CpG binding protein 2 (MECP2) is located at Xq28 and is a multifunctional gene with
ubiquitous expression. Loss-of-function mutations in MECP2 are associated with Rett …

Autism Spectrum Conditions (ASC) are a group of neurodevelopmental disorders
characterized by deficits in social communication and interaction as well as repetitive …

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with uncertain
origins. Understanding of the mechanisms underlying ASD remains limited, and treatments …

Extracting common patterns of neural circuit computations in the autism spectrum and
confirming them as a cause of specific core traits of autism is the first step toward identifying …

Abnormal neuronal and synapse growth is a core pathology resulting from deficiency of the
Fragile X mental retardation protein (FMRP), but molecular links underlying the excessive …