Role of macrophages in pregnancy and related complications

MK Jena, N Nayak, K Chen, NR Nayak - Archivum immunologiae et …, 2019 - Springer
Macrophages (MФs) are the leukocytes produced from differentiation of monocytes and are
located in almost all tissues of human body. They are involved in various processes, such as …

Circulating miRNAs and preeclampsia: from implantation to epigenetics

SR Giannubilo, M Cecati, D Marzioni… - International Journal of …, 2024 - mdpi.com
In this review, we comprehensively present the literature on circulating microRNAs
(miRNAs) associated with preeclampsia, a pregnancy-specific disease considered the …

CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia

L Przybyl, N Haase, M Golic, J Rugor… - Circulation …, 2016 - Am Heart Assoc
Rationale: We hypothesized that cluster of differentiation 74 (CD74) downregulation on
placental macrophages, leading to altered macrophage-trophoblast interaction, is involved …

Pro-inflammatory profile of preeclamptic placental mesenchymal stromal cells: new insights into the etiopathogenesis of preeclampsia

A Rolfo, D Giuffrida, AM Nuzzo, D Pierobon… - PLoS …, 2013 - journals.plos.org
The objective of the present study was to evaluate whether placental mesenchymal stromal
cells (PDMSCs) derived from normal and preeclamptic (PE) chorionic villous tissue …

[PDF][PDF] Maternal thyroid dysfunction affects placental profile of inflammatory mediators and the intrauterine trophoblast migration kinetics

JF Silva, NM Ocarino, R Serakides - Reproduction, 2014 - Citeseer
The objective of the present study was to evaluate the gene and immunohistochemical
expression of inflammatory mediators involved in the immune activity and the intrauterine …

Association of maternal thyroid peroxidase antibody during pregnancy with placental morphology and inflammatory and oxidative stress responses

X Ru, M Yang, Y Teng, Y Han, Y Hu, J Wang… - Frontiers in …, 2023 - frontiersin.org
Background Studies suggest that thyroid peroxidase antibody (TPOAb) positivity exposure
during pregnancy may contribute to changes in placental morphology and pathophysiology …

IL-1β and TGF-β weaken the placental barrier through destruction of tight junctions: An in vivo and in vitro study

G Tossetta, F Paolinelli, C Avellini, E Salvolini… - Placenta, 2014 - Elsevier
Introduction Chorioamnionitis is a gestational pathological condition characterized by acute
inflammation of the amniochorionic membranes and placentas leading to high …

[PDF][PDF] Bisphenol A modulates receptivity and secretory function of human decidual cells: an in vitro study

C Mannelli, AZ Szostek, K Lukasik, C Carotenuto… - …, 2015 - researchgate.net
The human endometrium is a fertility-determining tissue and a target of steroid hormones'
action. Endocrine disruptors (EDs) can exert adverse effects on the physiological function of …

Biological tools to study the effects of environmental contaminants at the feto–maternal interface

C Mannelli, F Ietta, AM Avanzati… - Dose …, 2015 - journals.sagepub.com
The identification of reproductive toxicants is a major scientific challenge for human health.
Prenatal life is the most vulnerable and important time span of human development. For …

Italian Advisory Board: sFlt-1/PlGF ratio and preeclampsia, state of the art and developments in diagnostic, therapeutic and clinical management

D Di Martino, I Cetin, T Frusca, E Ferrazzi… - European journal of …, 2016 - Elsevier
Extensive research has been published, showing the usefulness of angiogenic markers in
both diagnosis and subsequent prediction and management of preeclampsia and placenta …