Combining scattering experiments and colloid theory to characterize charge effects in concentrated antibody solutions
A Gulotta, M Polimeni, S Lenton, CG Starr… - Molecular …, 2024 - ACS Publications
Charges and their contribution to protein–protein interactions are essential for the key
structural and dynamic properties of monoclonal antibody (mAb) solutions. In fact, they …
structural and dynamic properties of monoclonal antibody (mAb) solutions. In fact, they …
Flow Activation Energy of High-Concentration Monoclonal Antibody Solutions and Protein–Protein Interactions Influenced by NaCl and Sucrose
The solution viscosity and protein–protein interactions (PPIs) as a function of temperature (4–
40° C) were measured at a series of protein concentrations for a monoclonal antibody (mAb) …
40° C) were measured at a series of protein concentrations for a monoclonal antibody (mAb) …