Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology

J Yang, A Griffin, Z Qiang, J Ren - Signal transduction and targeted …, 2022 - nature.com
Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …

Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies

K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

Mesoporous silica nanoparticles for drug delivery: Current insights

M Vallet-Regí, M Colilla, I Izquierdo-Barba, M Manzano - Molecules, 2017 - mdpi.com
This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug
delivery systems. Their intrinsic structural, textural and chemical features permit to design …

Nanoplatform-based cascade engineering for cancer therapy

J Chen, Y Zhu, C Wu, J Shi - Chemical Society Reviews, 2020 - pubs.rsc.org
Various therapeutic techniques have been studied for treating cancer precisely and
effectively, such as targeted drug delivery, phototherapy, tumor-specific catalytic therapy …

Gated materials for on-command release of guest molecules

E Aznar, M Oroval, L Pascual, JR Murguía… - Chemical …, 2016 - ACS Publications
Multidisciplinary research at the forefront of the field of hybrid materials has paved the way to
the development of endless examples of smart devices. One appealing concept in this fertile …

Cancer cell nucleus-targeting nanocomposites for advanced tumor therapeutics

L Pan, J Liu, J Shi - Chemical society reviews, 2018 - pubs.rsc.org
Tumor therapeutic efficacy is determined, to a great extent, by the delivery efficiency of
therapeutic drugs to their final targets. The cell nucleus has been proven to be the main …

Boosting cancer therapy with organelle-targeted nanomaterials

P Gao, W Pan, N Li, B Tang - ACS applied materials & interfaces, 2019 - ACS Publications
The ultimate goal of cancer therapy is to eliminate malignant tumors while causing no
damage to normal tissues. In the past decades, numerous nanoagents have been employed …

[HTML][HTML] Molecular targets, therapeutic agents and multitasking nanoparticles to deal with cancer stem cells: A narrative review

A Doustmihan, M Fathi, MA Mazloomi, A Salemi… - Journal of Controlled …, 2023 - Elsevier
There is increasing evidence that malignant tumors are initiated and maintained by a sub-
population of tumor cells that have similar biological properties to normal adult stem cells …

Precise design strategies of nanomedicine for improving cancer therapeutic efficacy using subcellular targeting

X Fu, Y Shi, T Qi, S Qiu, Y Huang, X Zhao… - Signal transduction and …, 2020 - nature.com
Therapeutic efficacy against cancer relies heavily on the ability of the therapeutic agents to
reach their final targets. The optimal targets of most cancer therapeutic agents are usually …