E. coli is most preferred system used for the production of recombinant proteins in bacteria
and the availability of improved genetic tools/methods are making it more valuable than …

With the current biotherapeutic market dominated by antibody molecules, bispecific
antibodies represent a key component of the next-generation of antibody therapy. Bispecific …

Escherichia coli is one of the organisms of choice for the production of recombinant proteins.
Its use as a cell factory is well-established and it has become the most popular expression …

Proteins are now widely produced in diverse microbial cell factories. The Escherichia coli is
still the dominant host for recombinant protein production but, as a bacterial cell, it also has …

The soluble expression of heterologous proteins in Escherichia coli remains a serious
bottleneck in protein production. Although alteration of expression conditions can sometimes …

Different species of microorganisms including yeasts, filamentous fungi and bacteria have
been used in the past 25 years for the controlled production of foreign proteins of scientific …

Expression of recombinant proteins in Escherichia coli (E. coli) remains the most popular
and cost-effective method for producing proteins in basic research and for pharmaceutical …

When massively expressed in bacteria, recombinant proteins often tend to misfold and
accumulate as soluble and insoluble nonfunctional aggregates. A general strategy to …

Background Disulfide bonds are one of the most common post-translational modifications
found in proteins. The production of proteins that contain native disulfide bonds is …

Protein complexes are responsible for key biological processes, but methods to produce
recombinant protein complexes for biochemical and biophysical studies are limited. We …