In the mosquito–human life cycle, the six species of malaria parasites infecting humans
(Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale wallickeri, Plasmodium …

Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

Recent reports of increased tolerance to artemisinin derivatives—the most recently adopted
class of antimalarials—have prompted a need for new treatments. The spirotetrahydro-β …

Plasmodium falciparum and Plasmodium vivax account for more than 95% of all human
malaria infections, and thus pose a serious public health challenge. To control and …

Abstract PlasmoDB (http://PlasmoDB. org) is a functional genomic database for Plasmodium
spp. that provides a resource for data analysis and visualization in a gene-by-gene or …

Next generation sequencing (NGS) combined with bioinformatics has successfully been
used in a vast array of analyses for infectious disease research of public health relevance …

Malaria elimination strategies require surveillance of the parasite population for genetic
changes that demand a public health response, such as new forms of drug resistance,. Here …

Despite great international efforts, malaria still inflicts an enormous toll on human lives,
especially in Africa. Throughout history, antimalarial medicines have been one of the most …

Plasmodium falciparum resistance to chloroquine, the former gold standard antimalarial
drug, is mediated primarily by mutant forms of the chloroquine resistance transporter …

Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …