Horizontal gene exchange in environmental microbiota

RI Aminov - Frontiers in microbiology, 2011 - frontiersin.org
Horizontal gene transfer (HGT) plays an important role in the evolution of life on the Earth.
This view is supported by numerous occasions of HGT that are recorded in the genomes of …

Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste

JC Chee‐Sanford, RI Mackie, S Koike… - Journal of …, 2009 - Wiley Online Library
Antibiotics are used in animal livestock production for therapeutic treatment of disease and
at subtherapeutic levels for growth promotion and improvement of feed efficiency. It is …

Evolution and ecology of antibiotic resistance genes

RI Aminov, RI Mackie - FEMS microbiology letters, 2007 - academic.oup.com
A new perspective on the topic of antibiotic resistance is beginning to emerge based on a
broader evolutionary and ecological understanding rather than from the traditional …

Pseudomonas 2.0: genetic upgrading of P. putida KT2440 as an enhanced host for heterologous gene expression

E Martínez-García, PI Nikel, T Aparicio… - Microbial cell …, 2014 - Springer
Background Because of its adaptability to sites polluted with toxic chemicals, the model soil
bacterium Pseudomonas putida is naturally endowed with a number of metabolic and stress …

Mutation as a stress response and the regulation of evolvability

RS Galhardo, PJ Hastings… - Critical reviews in …, 2007 - Taylor & Francis
Our concept of a stable genome is evolving to one in which genomes are plastic and
responsive to environmental changes. Growing evidence shows that a variety of …

Stress-induced mutagenesis in bacteria

PL Foster - Critical reviews in biochemistry and molecular biology, 2007 - Taylor & Francis
Bacteria spend their lives buffeted by changing environmental conditions. To adapt to and
survive these stresses, bacteria have global response systems that result in sweeping …

[PDF][PDF] Gamblers: an antibiotic-induced evolvable cell subpopulation differentiated by reactive-oxygen-induced general stress response

JP Pribis, L García-Villada, Y Zhai, O Lewin-Epstein… - Molecular cell, 2019 - cell.com
Antibiotics can induce mutations that cause antibiotic resistance. Yet, despite their
importance, mechanisms of antibiotic-promoted mutagenesis remain elusive. We report that …

Laboratory evolution reveals the metabolic and regulatory basis of ethylene glycol metabolism by Pseudomonas putida KT2440

WJ Li, LN Jayakody, MA Franden… - Environmental …, 2019 - Wiley Online Library
Pollution from ethylene glycol, and plastics containing this monomer, represent a significant
environmental problem. The investigation of its microbial metabolism therefore provides …

Stress-induced mutagenesis: implications in cancer and drug resistance

DM Fitzgerald, PJ Hastings… - Annual review of cancer …, 2017 - annualreviews.org
Genomic instability underlies many cancers and generates genetic variation that drives
cancer initiation, progression, and therapy resistance. In contrast with classical assumptions …

The Tn3‐family of Replicative Transposons

E Nicolas, M Lambin, D Dandoy, C Galloy… - Mobile DNA …, 2015 - Wiley Online Library
The ampicillin‐resistance transposon Tn3is the archetype (“Tn3” being synonymous with
“Tn1” or “Tn2”;(1)) of a large and widespread family of transposons with representatives in …