[HTML][HTML] What makes a centromere?

PB Talbert, S Henikoff - Experimental cell research, 2020 - Elsevier
Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and
attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and …

Centromere repeats: hidden gems of the genome

G Hartley, RJ O'Neill - Genes, 2019 - mdpi.com
Satellite DNAs are now regarded as powerful and active contributors to genomic and
chromosomal evolution. Paired with mobile transposable elements, these repetitive …

Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post‐genome era

T Raudsepp, CJ Finno, RR Bellone… - Animal …, 2019 - Wiley Online Library
The horse reference genome from the Thoroughbred mare Twilight has been available for a
decade and, together with advances in genomics technologies, has led to unparalleled …

Human centromere repositioning activates transcription and opens chromatin fibre structure

C Naughton, C Huidobro, CR Catacchio… - Nature …, 2022 - nature.com
Human centromeres appear as constrictions on mitotic chromosomes and form a platform for
kinetochore assembly in mitosis. Biophysical experiments led to a suggestion that repetitive …

The localization of centromere protein A is conserved among tissues

E Cappelletti, FM Piras, L Sola, M Santagostino… - Communications …, 2023 - nature.com
Centromeres are epigenetically specified by the histone H3 variant CENP-A. Although
mammalian centromeres are typically associated with satellite DNA, we previously …

Induction of spontaneous human neocentromere formation and long-term maturation

M Murillo-Pineda, LP Valente, M Dumont… - Journal of Cell …, 2021 - rupress.org
Human centromeres form primarily on α-satellite DNA but sporadically arise de novo at
naive ectopic loci, creating neocentromeres. Centromere inheritance is driven primarily by …

Chromosomal polymorphism in mammals: an evolutionary perspective

G Dobigny, J Britton‐Davidian… - Biological Reviews, 2017 - Wiley Online Library
Although chromosome rearrangements (CRs) are central to studies of genome evolution,
our understanding of the evolutionary consequences of the early stages of karyotypic …

Robertsonian fusion and centromere repositioning contributed to the formation of satellite-free centromeres during the evolution of zebras

E Cappelletti, FM Piras, L Sola… - Molecular Biology …, 2022 - academic.oup.com
Centromeres are epigenetically specified by the histone H3 variant CENP-A and typically
associated with highly repetitive satellite DNA. We previously discovered natural satellite …

Birth, evolution, and transmission of satellite-free mammalian centromeric domains

SG Nergadze, FM Piras, R Gamba, M Corbo… - Genome …, 2018 - genome.cshlp.org
Mammalian centromeres are associated with highly repetitive DNA (satellite DNA), which
has so far hindered molecular analysis of this chromatin domain. Centromeres are …

From evolution to function: Two sides of the same CENP-B coin?

R Gamba, D Fachinetti - Experimental Cell Research, 2020 - Elsevier
The centromere is the nucleoproteic chromosomal structure necessary for accurate
chromosome segregation during cell division. One of the earliest centromeric proteins to be …