Antibiotic perturbations to the gut microbiome
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
Next-generation sequencing: insights to advance clinical investigations of the microbiome
CR Wensel, JL Pluznick, SL Salzberg… - The Journal of clinical …, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …
human microbiome by allowing for the discovery and characterization of unculturable …
A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia
The emerging understanding of gut microbiota as 'metabolic machinery'influencing many
aspects of physiology has gained substantial attention in the field of psychiatry. This is …
aspects of physiology has gained substantial attention in the field of psychiatry. This is …
Metagenomics of Parkinson's disease implicates the gut microbiome in multiple disease mechanisms
Parkinson's disease (PD) may start in the gut and spread to the brain. To investigate the role
of gut microbiome, we conducted a large-scale study, at high taxonomic resolution, using …
of gut microbiome, we conducted a large-scale study, at high taxonomic resolution, using …
The gut microbiome and hypertension
A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …
microbiome in the regulation of blood pressure. The field has moved from association to …
Challenges and opportunities in sharing microbiome data and analyses
Microbiome data, metadata and analytical workflows have become 'big'in terms of volume
and complexity. Although the infrastructure and technologies to share data have been …
and complexity. Although the infrastructure and technologies to share data have been …
Gut microbiota and their metabolites in stroke: a double-edged sword
Besides damaging the brain, stroke causes systemic changes, including to the
gastrointestinal system. A growing body of evidence supports the role of the gut and its …
gastrointestinal system. A growing body of evidence supports the role of the gut and its …
Gut microbiota composition is related to AD pathology
BJH Verhaar, HMA Hendriksen, FA de Leeuw… - Frontiers in …, 2022 - frontiersin.org
Introduction Several studies have reported alterations in gut microbiota composition of
Alzheimer's disease (AD) patients. However, the observed differences are not consistent …
Alzheimer's disease (AD) patients. However, the observed differences are not consistent …
Gut dysbiosis promotes preeclampsia by regulating macrophages and trophoblasts
J Jin, L Gao, X Zou, Y Zhang, Z Zheng… - Circulation …, 2022 - Am Heart Assoc
Background: Preeclampsia is one of the leading causes of maternal and perinatal morbidity
and is characterized by hypertension, inflammation, and placental dysfunction. Gut …
and is characterized by hypertension, inflammation, and placental dysfunction. Gut …