Designing bioresponsive nanomaterials for intracellular self-assembly

S Chagri, DYW Ng, T Weil - Nature Reviews Chemistry, 2022 - nature.com
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …

A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly

SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Supramolecular self‐assembly in living cells

M Dergham, S Lin, J Geng - Angewandte Chemie, 2022 - Wiley Online Library
Supramolecular interactions rely on non‐covalent forces, such as hydrophobic effects,
hydrogen‐bonding, and electrostatic interactions, which govern many intracellular biological …

Research progress on self-assembled nanodrug delivery systems

L Qiao, H Yang, S Gao, L Li, X Fu, Q Wei - Journal of materials …, 2022 - pubs.rsc.org
In recent years, nanodrug delivery systems have attracted increasing attention due to their
advantages, such as high drug loading, low toxicity and side effects, improved …

Deep insight of design, mechanism, and cancer theranostic strategy of nanozymes

L Yang, S Dong, S Gai, D Yang, H Ding, L Feng… - Nano-Micro Letters, 2024 - Springer
Since the discovery of enzyme-like activity of Fe3O4 nanoparticles in 2007, nanozymes are
becoming the promising substitutes for natural enzymes due to their advantages of high …

Activatable Graphene Quantum‐Dot‐Based Nanotransformers for Long‐Period Tumor Imaging and Repeated Photodynamic Therapy

Y Yang, B Wang, X Zhang, H Li, S Yue… - Advanced …, 2023 - Wiley Online Library
Photodynamic therapy (PDT) is considered as an emerging therapeutic modality against
cancer with high spatiotemporal selectivity because the utilized photosensitizers (PSs) are …

Smart nanozyme platform with activity‐correlated ratiometric molecular imaging for predicting therapeutic effects

L Teng, X Han, Y Liu, C Lu, B Yin, S Huan… - Angewandte …, 2021 - Wiley Online Library
Nanozymes with intrinsic enzyme‐like characteristics have attracted enormous research
interest in biological application. However, there is a lack of facile approach for evaluating …

Mitochondrial Localized In Situ Self‐Assembly Reprogramming Tumor Immune and Metabolic Microenvironment for Enhanced Cancer Therapy

Z Wang, Q Wang, H Cao, Z Wang, D Wang… - Advanced …, 2024 - Wiley Online Library
The inherent immune and metabolic tumor microenvironment (TME) of most solid tumors
adversely affect the antitumor efficacy of various treatments, which is an urgent issue to be …

In vivo self‐assembly induced cell membrane phase separation for improved peptide drug internalization

RC Guo, XH Zhang, PS Fan, BL Song… - Angewandte Chemie …, 2021 - Wiley Online Library
Therapeutic peptides have been widely concerned, but their efficacy is limited by the
inability to penetrate cell membranes, which is a key bottleneck in peptide drugs delivery …

Smart One‐for‐All Agent with Adaptive Functions for Improving Photoacoustic/Fluorescence Imaging‐Guided Photodynamic Immunotherapy

H Gao, X Qi, J Zhang, N Wang, J Xin, D Jiao… - Small …, 2023 - Wiley Online Library
Multifunctional phototheranostics that integrate several diagnostic and therapeutic strategies
into one platform hold great promise for precision medicine. However, it is really difficult for …