Obesity is a state of low-grade chronic inflammation that causes multiple metabolic
diseases. During obesity, signalling via cytokines of the TNF family mediate cell death and …

The expansion of adipose tissue (AT) in obesity is accompanied by the accumulation of
immune cells that contribute to a state of low‐grade, chronic inflammation and dysregulated …

Adipose tissue not only has an important role in the storage of excess nutrients but also
senses nutrient status and regulates energy mobilization. An overall positive energy balance …

Both obesity and aging are associated with the development of metabolic diseases such as
type 2 diabetes and cardiovascular disease. Chronic low-grade inflammation of adipose …

The prevalence of obesity has recently increased dramatically and has contributed to the
increasing prevalence of various pathological conditions, including type 2 diabetes mellitus …

Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …

Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …

The composition of the gut microbiota and excessive ingestion of high‐fat diets (HFD) are
considered to be important factors for development of obesity. In this review we describe a …

The adipose tissue is a central metabolic organ in the regulation of whole-body energy
homeostasis. The white adipose tissue functions as a key energy reservoir for other organs …