Medicinal chemistry of oxazines as promising agents in drug discovery

DS Zinad, A Mahal, RK Mohapatra… - Chemical biology & …, 2020 - Wiley Online Library
Oxazines have brought much synthetic interest due to their extensive biological activities.
These are the important category of heterocycles, which may be formally derived from …

[PDF][PDF] A review on current synthetic strategies of oxazines

SL Gaonkar, VU Nagaraj, S Nayak - Mini-Reviews in Organic …, 2019 - researchgate.net
In the past three decades, the heterocyclic oxazine cores have been intensely concerned.
Oxazine derivatives are promising vital heterocyclic motifs. They are eminent for their …

Novel piperazine-1, 2, 3-triazole leads for the potential treatment of pancreatic cancer

J Sun, JR Baker, CC Russell, HNT Pham… - RSC medicinal …, 2023 - pubs.rsc.org
From lead 1,(N-(4-((4-(3-(4-(3-methoxyphenyl)-1H-1, 2, 3-triazol-1-yl) propyl) piperazin-1-yl)
sulfonyl)-phenyl) acetamide), a S100A2–p53 protein–protein interaction inhibitor based on …

In situ epoxide generation by dimethyldioxirane oxidation and the use of epichlorohydrin in the flow synthesis of a library of β-amino alcohols

PJ Cossar, JR Baker, N Cain… - Royal Society open …, 2018 - royalsocietypublishing.org
The flow coupling of epichlorohydrin with substituted phenols, while efficient, limits the
nature of the epoxide available for the development of focused libraries of β-amino alcohols …

[PDF][PDF] NATURAL AND SYNTHETIC SUBSTANCES IN THE ENVIRONMENT: A COMPENDIUM ON POLICY ASSESSMENT, INSIGHTS AND IMPLICATIONS

O Ayejuyo, C Isanbor, A Abayomi - 2021 - researchgate.net
Benzoxazinones are secondary metabolites found in gramineous plants, such as Zea mays.
They are involved in the chemical defence of plants against pathogens and insects, and …