Proteomic analysis of cells, tissues and body fluids has generated valuable insights into the
complex processes influencing human biology. Proteins represent intermediate phenotypes …

A dominant area of antibody research is the extension of the use of this mighty experimental
and therapeutic tool for the specific detection of molecules for diagnostics, visualization, and …

Forward genetic screens with CRISPR–Cas9 genome editing enable high-resolution
detection of genetic vulnerabilities in cancer cells. We conducted genome-wide CRISPR …

Comprehensive profiling of humoral antibody response to severe acute respiratory
syndrome (SARS) coronavirus-2 (CoV-2) proteins is essential in understanding the host …

Recombinant antibodies are highly specific detection probes in research, diagnostics, and
have emerged over the last two decades as the fastest growing class of therapeutic proteins …

Background: The latest research identified cuproptosis as an entirely new mechanism of cell
death. However, as a key regulator in copper-induced cell death, the prognostic and …

Molecular recognition reagents are key tools for understanding biological processes and are
used universally by scientists to study protein expression, localisation and interactions …

Identifying the interactions established by a protein of interest can be a critical step in
understanding its function. This is especially true when an unknown protein of interest is …

Programmed death 1 (PD-1) and its two natural ligands PD-L1 and PD-L2 are responsible
for delivering inhibitory signals that regulate the balance between T cell activation …

Today, it is widely appreciated that protein–protein interactions play a fundamental role in
biological processes. This was not always the case. The study of protein interactions started …