Reports of the increasing incidence of male infertility paired with decreasing semen quality
have triggered studies on the effects of lifestyle and environmental factors on the male …

This review presents a holistic overview of the occurrence, mobilization, and pathways of
arsenic (As) from predominantly geogenic sources into different near-surface environmental …

Chronic kidney disease (CKD) has a high prevalence in the general population and is
associated with high mortality; a need therefore exists for better biomarkers for diagnosis …

The primary adrenal cortical steroid hormones, aldosterone, and the glucocorticoids cortisol
and corticosterone, act through the structurally similar mineralocorticoid (MR) and …

Testosterone is one of the most potent naturally secreted androgenicanabolic hormones,
and its biological effects include promotion of muscle growth. In muscle, testosterone …

Reproduction and fertility are regulated via hormones of the hypothalamic‐pituitary‐gonadal
(HPG) axis. Control of this reproductive axis occurs at all levels, including the brain and …

Alongside an increasing prevalence of couple and male infertility, evidence suggests there
is a global declining trend in male fertility parameters over the past few decades. This may …

Ancestral environmental exposures have previously been shown to promote epigenetic
transgenerational inheritance and influence all aspects of an individual's life history. In …

Masculinization depends on adequate production of testosterone by the fetal testis within a
specific “masculinization programming window.” Disorders resulting from subtle deficiencies …

Zinc deficiency is prevalent throughout the world, including the USA. Severe and moderate
deficiency of zinc is associated with hypogonadism in men. However, the effect of marginal …