The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

Found throughout biology, polyvalent interactions are characterized by the simultaneous
binding of multiple ligands on one biological entity to multiple receptors on another (top part …

The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins
has been implicated in various intercellular-adhesion and intracellular-signalling-mediated …

The molecular mechanisms used by the gonococcus to initiate infection exhibit gender
specificity. The clinical presentations of disease are also strikingly different upon comparison …

Überall in der Biologie kommen polyvalente Wechselwirkungen vor. Sie zeichnen sich
durch die gleichzeitige Bindung mehrerer Liganden einer biologischen Einheit an mehrere …

Pili of Neisseria gonorrhoeae and Neisseria meningitidis mediate binding of the bacteria to
human cell‐surface receptors. We found that purified pili bound to a 55‐to 60‐kDa doublet …

Over the last few years, dramatic increases in our knowledge about diffusely adhering
Escherichia coli (DAEC) pathogenesis have taken place. The typical class of DAEC includes …

Invasion of human mucosal cells by N. gonorrhoeae via the binding to heparansulfate
proteoglycan receptors is considered a crucial event of the infection. Using different human …

Infection with Neisseria gonorrhoeae can trigger an intense inflammatory response, yet
there is little specific immune response or development of immune memory. In addition …

▪ Abstract The closely related bacterial pathogens Neisseria gonorrhoeae (gonococci, GC)
and N. meningitidis (meningococci, MC) initiate infection at human mucosal epithelia …