[HTML][HTML] Insights into amentoflavone: a natural multifunctional biflavonoid

X Xiong, N Tang, X Lai, J Zhang, W Wen, X Li… - Frontiers in …, 2021 - frontiersin.org
Amentoflavone is an active phenolic compound isolated from Selaginella tamariscina over
40 years. Amentoflavone has been extensively recorded as a molecule which displays …

[HTML][HTML] Enzyme activity of natural products on cytochrome P450

HL Zuo, HY Huang, YCD Lin, XX Cai, XJ Kong, DL Luo… - Molecules, 2022 - mdpi.com
Drug-metabolizing enzymes, particularly the cytochrome P450 (CYP450) monooxygenases,
play a pivotal role in pharmacokinetics. CYP450 enzymes can be affected by various …

[HTML][HTML] Garcinia kola: a critical review on chemistry and pharmacology of an important West African medicinal plant

J Tauchen, A Frankova, A Manourova, I Valterova… - Phytochemistry …, 2023 - Springer
Abstract Garcinia kola Heckel (Clusiaceae) is a tree indigenous to West and Central Africa.
All plant parts, but especially the seeds, are of value in local folklore medicine. Garcinia kola …

[HTML][HTML] Proceedings of chemistry, pharmacology, pharmacokinetics and synthesis of biflavonoids

X He, F Yang, X Huang - Molecules, 2021 - mdpi.com
Biflavonoids, composed of two monoflavonoid residues, occur naturally in angiosperms,
bryophytes, ferns, and gymnosperms. More than 592 biflavonoids have been structurally …

The traditional and modern uses of Selaginella tamariscina (P. Beauv.) Spring, in medicine and cosmetic: Applications and bioactive ingredients

C Bailly - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Extracts of the plant Selaginella tamariscina (P. Beauv.)
Spring (spike moss) are used for a long time in Asia, for the treatment of multiple diseases …

Rottlerin renders a selective and highly potent CYP2C8 inhibition to impede EET formation for implication in cancer therapy

D Manhas, S Bhatt, G Rai, V Kumar, S Bharti… - Chemico-biological …, 2023 - Elsevier
CYP2C8 is a crucial CYP isoform responsible for the metabolism of xenobiotics and
endogenous molecules. CYP2C8 converts arachidonic acid to epoxyeicosatrienoic acids …

Homogenate-Ultrasound-Assisted Ionic Liquid Extraction of Total Flavonoids from Selaginella involven: Process Optimization, Composition Identification, and …

J Lei, L Zhu, Y Zheng, M Yu, G Li, F Zhang, L Linghu… - ACS …, 2021 - ACS Publications
In this paper, an efficient approach to extract total flavonoids (TFs) from Selaginella
involvens (Sw.) Spring using homogenate-ultrasound-assisted ionic liquid (IL) extraction …

[HTML][HTML] Potential of amentoflavone with antiviral properties in COVID-19 treatment

AV Singh - Asian Biomedicine, 2021 - sciendo.com
Amentoflavone is one of the flavonoids that are known for their antiviral effects and many of
them are predicted to have inhibitory effects against severe acute respiratory syndrome …

[HTML][HTML] Comprehensive investigation of stereoselective food drug interaction potential of resveratrol on nine P450 and six UGT isoforms in human liver microsomes

SB Ji, SY Park, S Bae, HJ Seo, SE Kim, GM Lee, Z Wu… - Pharmaceutics, 2021 - mdpi.com
The stereoselectivity of the food drug inhibition potential of resveratrol on cytochrome P450s
and uridine 5′-diphosphoglucuronosyl transferases was investigated in human liver …

[HTML][HTML] Potent and selective inhibition of CYP1A2 enzyme by obtusifolin and its chemopreventive effects

EJ Park, K Park, P Durai, KY Kim, SY Park, J Kwon… - Pharmaceutics, 2022 - mdpi.com
Obtusifolin, a major anthraquinone component present in the seeds of Cassia tora, exhibits
several biological activities, including the amelioration of memory impairment, prevention of …