Melittin, the main venom component of the European Honeybee, is a cationic linear peptide-
amide of 26 amino acid residues with the sequence: GIGAVLKVLTTGLPALISWIKRKRQQ …

As one of the most serious threats to human being, cancer is hard to be treated when
metastasis happens. What's worse, there are few identified targets of metastasis for drug …

Abstract Design of effective nanomedicines to modulate multiple immune cells to overcome
the immune‐suppressive tumor microenvironment is desirable to improve the overall poor …

This article reviews the most important advances in the enzymatic synthesis of polyesters. In
first place, the different processes of polyester enzymatic synthesis, ie, polycondensation …

Cancer immunotherapy has witnessed significant advances in the past decade, however
challenges associated with immune‐related adverse effects and immunosuppressive tumor …

As a naturally occurring cytolytic peptide, melittin (MLT) not only exhibits a potent direct
tumor cell-killing effect but also possesses various immunomodulatory functions. MLT shows …

Melittin (MLT) has been studied preclinically as an anticancer agent based on its broad lytic
effects in multiple tumor types. However, unsatisfactory tissue distribution, hemolysis, rapid …

Poly (β-amino ester) s (PβAE) s are considered as the most potent alternative to viral
vectors, which has been increasingly proposed for targeting gene delivery, because of their …

Metastasis accounts for greater than 90% of cancer-related deaths. Despite recent
advancements in conventional chemotherapy, immunotherapy, targeted therapy, and their …

Ischemic stroke is a leading cause of death and disability and remains without effective
treatment options. Improved treatment of stroke requires efficient delivery of multimodal …