Engineering biological nanopore approaches toward protein sequencing

X Wei, T Penkauskas, JE Reiner, C Kennard… - ACS …, 2023 - ACS Publications
Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

The application of single molecule nanopore sensing for quantitative analysis

Y Wu, JJ Gooding - Chemical Society Reviews, 2022 - pubs.rsc.org
Nanopore-based sensors typically work by monitoring transient pulses in conductance via
current–time traces as molecules translocate through the nanopore. The unique property of …

A rolling circle-amplified G-quadruplex/hemin DNAzyme for chemiluminescence immunoassay of the SARS-CoV-2 protein

R Zhang, J Wu, H Ao, J Fu, B Qiao, Q Wu… - Analytical …, 2021 - ACS Publications
Sensitive detection of the SARS-CoV-2 protein remains a great research interest in clinical
screening and diagnosis owing to the coronavirus epidemic. Here, an ultrasensitive …

An electrochemical immunosensor using SARS-CoV-2 spike protein-nickel hydroxide nanoparticles bio-conjugate modified SPCE for ultrasensitive detection of SARS …

Z Rahmati, M Roushani, H Hosseini, H Choobin - Microchemical Journal, 2021 - Elsevier
As a promising approach for serological tests, the present study aimed at designing a robust
electrochemical biosensor for selective and quantitative analysis of SARS‐CoV‐2-specific …

Progress in electrochemical biosensing of SARS-CoV-2 virus for COVID-19 management

MM Rahman - Chemosensors, 2022 - mdpi.com
Rapid and early diagnosis of lethal coronavirus disease-19 (COVID-19) caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important issue …

A click chemistry amplified nanopore assay for ultrasensitive quantification of HIV-1 p24 antigen in clinical samples

X Wei, X Wang, Z Zhang, Y Luo, Z Wang… - Nature …, 2022 - nature.com
Despite major advances in HIV testing, ultrasensitive detection of early infection remains
challenging, especially for the viral capsid protein p24, which is an early virological …

Gold nanoparticle-mediated lateral flow assays for detection of host antibodies and COVID-19 proteins

LS Ardekani, PW Thulstrup - Nanomaterials, 2022 - mdpi.com
Coronaviruses, that are now well-known to the public, include a family of viruses that can
cause severe acute respiratory syndrome (SARS) and other respiratory diseases, such as …

Nanopore single-molecule analysis of biomarkers: Providing possible clues to disease diagnosis

X Chen, S Zhou, Y Wang, L Zheng, S Guan… - TrAC Trends in …, 2023 - Elsevier
Biomarker detection has attracted increasing interest in recent years due to the minimally or
non-invasive sampling process. Single entity analysis of biomarkers is expected to provide …

Bio-conjugated nanoarchitectonics with dual-labeled nanoparticles for a colorimetric and fluorescent dual-mode serological lateral flow immunoassay sensor in …

SK Kim, JU Lee, MJ Jeon, SK Kim, SH Hwang… - RSC …, 2023 - pubs.rsc.org
Serological detection of antibodies for diagnosing infectious diseases has advantages in
facile diagnostic procedures, thereby contributing to controlling the spread of the pathogen …

Electrochemical immunosensors based on zinc oxide nanorods for detection of antibodies against SARS-CoV-2 spike protein in convalescent and vaccinated …

FA Nunez, ACH Castro, VL de Oliveira… - ACS Biomaterials …, 2022 - ACS Publications
Even after over 2 years of the COVID-19 pandemic, research on rapid, inexpensive, and
accurate tests remains essential for controlling and avoiding the global spread of SARS-CoV …