[HTML][HTML] Microneedles for advanced ocular drug delivery

K Glover, D Mishra, S Gade, LK Vora, Y Wu… - Advanced drug delivery …, 2023 - Elsevier
In the field of ocular drug delivery, topical delivery remains the most common treatment
option for managing anterior segment diseases, while intraocular injections are the current …

Scleral structure and biomechanics

C Boote, IA Sigal, R Grytz, Y Hua, TD Nguyen… - Progress in retinal and …, 2020 - Elsevier
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …

Determination of Corneal Biomechanical Behavior in-vivo for Healthy Eyes Using CorVis ST Tonometry: Stress-Strain Index

A Eliasy, KJ Chen, R Vinciguerra, BT Lopes… - … in bioengineering and …, 2019 - frontiersin.org
Purpose: This study aims to introduce and clinically validate a new algorithm that can
determine the biomechanical properties of the human cornea in vivo. Methods: A parametric …

The dynamic sclera: extracellular matrix remodeling in normal ocular growth and myopia development

AR Harper, JA Summers - Experimental eye research, 2015 - Elsevier
Myopia is a common ocular condition, characterized by excessive elongation of the ocular
globe. The prevalence of myopia continues to increase, particularly among highly educated …

Aging and ocular tissue stiffness in glaucoma

B Liu, S McNally, JI Kilpatrick, SP Jarvis… - Survey of …, 2018 - Elsevier
Glaucoma is a progressive and chronic neurodegenerative disorder characterized by
damage to the inner layers of the retina and deformation of the optic nerve head. The …

Development and validation of a correction equation for Corvis tonometry

AA Joda, MMS Shervin, D Kook… - Computer methods in …, 2016 - Taylor & Francis
Primary objective: This study uses numerical analysis and validation against clinical data to
develop a method to correct intraocular pressure (IOP) measurements obtained using the …

Optic nerve head biomechanics in aging and disease

JC Downs - Experimental eye research, 2015 - Elsevier
This nontechnical review is focused upon educating the reader on optic nerve head
biomechanics in both aging and disease along two main themes: what is known about how …

Age-and race-related differences in human scleral material properties

R Grytz, MA Fazio, V Libertiaux, L Bruno… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: We tested the hypothesis that there are age-and race-related differences in
posterior scleral material properties, using eyes from human donors of European (20–90 …

Collagen structure and mechanical properties of the human sclera: analysis for the effects of age

B Coudrillier, J Pijanka, J Jefferys… - Journal of …, 2015 - asmedigitalcollection.asme.org
The objective of this study was to measure the collagen fiber structure and estimate the
material properties of 7 human donor scleras, from age 53 to 91. The specimens were …

Injectable biomedical devices for sensing and stimulating internal body organs

YH Jung, JU Kim, JS Lee, JH Shin, W Jung… - Advanced …, 2020 - Wiley Online Library
The rapid pace of progress in implantable electronics driven by novel technology has
created devices with unconventional designs and features to reduce invasiveness and …