The association between chronic inflammation and increased risk of cardiovascular disease
in rheumatoid arthritis (RA) is well established. In the general population, inflammation is an …

Clonal hematopoiesis arises from somatic mutations that provide a fitness advantage to
hematopoietic stem cells and the outgrowth of clones of blood cells. Clonal hematopoiesis …

Suppressing inflammation has been the primary focus of therapies in autoimmune rheumatic
diseases (AIRDs), including rheumatoid arthritis and systemic lupus erythematosus …

Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease, of which the leading
cause of death is cardiovascular disease (CVD). The levels of total cholesterol (TC), low …

Introduction Persistent and excess IL-6 production often contributes to a variety of immune
diseases. IL-6–targeting therapy was first approved for Castleman disease, then rheumatoid …

Rheumatoid arthritis (RA) carries significant risk for atherosclerotic cardiovascular disease
(ASCVD). Traditional ASCVD risk factors fail to account for this accelerated atherosclerosis …

Autoimmune diseases are associated with a dramatically increased risk of atherosclerotic
cardiovascular disease and its clinical manifestations. The increased risk is consistent with …

Background and aims Lipoprotein (a)[Lp (a)] and interleuking-6 (IL-6), an inflammation
biomarker, have been established as distinct targets of the residual atherosclerotic …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent
synovial inflammation and irreversible cartilage and bone damage. Despite its predominant …