[HTML][HTML] Antimicrobial peptides for combating drug-resistant bacterial infections

J Xuan, W Feng, J Wang, R Wang, B Zhang, L Bo… - Drug Resistance …, 2023 - Elsevier
The problem of drug resistance due to long-term use of antibiotics has been a concern for
years. As this problem grows worse, infections caused by multiple bacteria are expanding …

[HTML][HTML] The science of antibiotic discovery

K Lewis - Cell, 2020 - cell.com
We are experiencing an antimicrobial resistance (AMR) crisis, brought on by the drying up of
the antibiotic discovery pipeline and the resulting unchecked spread of resistant pathogens …

[HTML][HTML] Antimicrobial peptides: A potent alternative to antibiotics

M Rima, M Rima, Z Fajloun, JM Sabatier, B Bechinger… - Antibiotics, 2021 - mdpi.com
Antimicrobial peptides constitute one of the most promising alternatives to antibiotics since
they could be used to treat bacterial infections, especially those caused by multidrug …

[HTML][HTML] Focus: antimicrobial resistance: antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria

IE Mba, EI Nweze - The Yale journal of biology and medicine, 2022 - ncbi.nlm.nih.gov
Microbial resistance to antibiotics is an ancient and dynamic issue that has brought a
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …

[HTML][HTML] Lipid-based antimicrobial delivery-systems for the treatment of bacterial infections

DY Wang, HC Van der Mei, Y Ren, HJ Busscher… - Frontiers in …, 2020 - frontiersin.org
Many nanotechnology-based antimicrobials and antimicrobial-delivery-systems have been
developed over the past decades with the aim to provide alternatives to antibiotic treatment …

[HTML][HTML] Emerging peptide antibiotics with therapeutic potential

G Upert, A Luther, D Obrecht, P Ermert - Medicine in drug discovery, 2021 - Elsevier
This review covers some of the recent progress in the field of peptide antibiotics with a focus
on compounds with novel or established mode of action and with demonstrated efficacy in …

Recent progress of antibacterial natural products: Future antibiotics candidates

J Dai, R Han, Y Xu, N Li, J Wang, W Dan - Bioorganic chemistry, 2020 - Elsevier
The discovery of novel antibacterial molecules plays a key role in solving the current
antibiotic crisis issue. Natural products have long been an important source of drug …

The Challenge of Global Emergence of Novel Colistin-Resistant Escherichia coli ST131

M Taati Moghadam, M Mirzaei… - Microbial drug …, 2021 - liebertpub.com
Escherichia coli ST131 is one of the high-risk multidrug-resistant clones with a global
distribution and the ability to persist and colonize in a variety of niches. Carbapenemase …

[HTML][HTML] BrevicidineB, a new member of the brevicidine family, displays an extended target specificity

X Zhao, OP Kuipers - Frontiers in microbiology, 2021 - frontiersin.org
The group of bacterial non-ribosomally produced peptides (NRPs) has formed a rich source
for drug development. Brevicidine, a bacterial non-ribosomally produced cyclic lipo …

[HTML][HTML] Synergistic Activity of Capsaicin and Colistin Against Colistin-Resistant Acinetobacter baumannii: In Vitro/Vivo Efficacy and Mode of Action

T Guo, M Li, X Sun, Y Wang, L Yang, H Jiao… - Frontiers in …, 2021 - frontiersin.org
Acinetobacter baumannii is an opportunistic pathogen predominantly associated with
nosocomial infections. With emerging resistance against polymyxins, synergistic …