Digestive system diseases (DSD) are very complex conditions that severely threaten human
health. Therefore, there is an urgent need to develop new pharmacological treatment …

Holistic management of pancreatitis means that gastroenterologists in the 21st Century
should think beyond improving in-hospital outcomes of pancreatitis alone. In particular, there …

Abstract Background Chronic Pancreatitis (CP) causes morphological changes in the
pancreatic tissue, leading to complications and pain, which may require endoscopic …

Background Anxiety and depression are common psychological comorbidities in patients
with chronic pancreatitis (CP). There is still a lack of epidemiological studies on anxiety and …

Background Chronic pancreatitis (CP) is characterized by chronic abdominal pain and
functional insufficiency. However, a small subset of patients with prior acute pancreatitis (AP) …

Recurrent acute and chronic pancreatitis (RAP, CP) are complex, progressive inflammatory
diseases with variable pain experiences impacting patient function and quality of life. The …

Background/objectives The recently proposed “new mechanistic definition of chronic
pancreatitis (CP)” categorized early CP as a reversible condition. However, there is no clear …

Introduction Although abdominal pain is the most prevalent and disabling symptom in
patients with chronic pancreatitis (CP), there are also patients who have painless CP …

Background Silent chronic pancreatitis (SCP) is a poorly understood subtype of chronic
pancreatitis (CP) in which individuals describe little to no abdominal pain. The risk factors for …

Background: Considering the extensive innervation of the pulp tissue, asymptomatic
irreversible pulpitis (AIP) or “silent pulpitis” represents a confounding clinical condition …