Prior mouse genetic research has set the stage for a deep understanding of appetite
regulation. This goal is now being realized through the use of recent technological …

Objectives The National Institutes of Health, led by the National Heart, Lung, and Blood
Institute, organized a working group of experts to discuss the problem of weight regain after …

The ability to resist the urge to eat requires the proper functioning of neuronal circuits
involved in top-down control to oppose the conditioned responses that predict reward from …

Food is consumed in order to maintain energy balance at homeostatic levels. In addition,
palatable food is also consumed for its hedonic properties independent of energy status …

Dieting is the most common approach to losing weight for the majority of obese and
overweight individuals. Restricting intake leads to weight loss in the short term, but, by itself …

Food selection is primarily guided by the visual system. Multiple functional neuro-imaging
studies have examined the brain responses to visual food stimuli. However, the results of …

Neuroimaging is becoming increasingly common in obesity research as investigators try to
understand the neurological underpinnings of appetite and body weight in humans. Positron …

In healthy individuals, food cues can trigger hunger and feeding behavior. Likewise,
smoking cues can trigger craving and relapse in smokers. Brain imaging studies report that …

Although weight loss can usually be achieved by restricting food intake, the majority of
dieters regain weight over the long-term. In the hypothalamus, hormonal signals from the …

The conscious perception of the hedonic sensory properties of caloric foods is commonly
believed to guide our dietary choices. Current and traditional models implicate the …