Lipid transport and metabolism at the blood-brain interface: implications in health and disease
Many prospective studies have shown that a diet enriched in omega-3 polyunsaturated fatty
acids (n-3 PUFAs) can improve cognitive function during normal aging and prevent the …
acids (n-3 PUFAs) can improve cognitive function during normal aging and prevent the …
Perinatal dietary polyunsaturated fatty acids in brain development, role in neurodevelopmental disorders
M Martinat, M Rossitto, M Di Miceli, S Layé - Nutrients, 2021 - mdpi.com
n-3 and n-6 polyunsaturated fatty acids (PUFAs) are essential fatty acids that are provided
by dietary intake. Growing evidence suggests that n-3 and n-6 PUFAs are paramount for …
by dietary intake. Growing evidence suggests that n-3 and n-6 PUFAs are paramount for …
Immune response and blood–brain barrier dysfunction during viral neuroinvasion
Z Chen, G Li - Innate Immunity, 2021 - journals.sagepub.com
The blood-brain barrier (BBB), which protects the CNS from pathogens, is composed of
specialized brain microvascular endothelial cells (BMECs) joined by tight junctions and …
specialized brain microvascular endothelial cells (BMECs) joined by tight junctions and …
Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier
Breakdown of the blood-retinal barrier (BRB) causes retinal edema and vision loss. We
investigated the role of Wnt signaling in maintaining the BRB by limiting transcytosis. Mice …
investigated the role of Wnt signaling in maintaining the BRB by limiting transcytosis. Mice …
[HTML][HTML] Brain endothelial PTEN/AKT/NEDD4-2/MFSD2A axis regulates blood-brain barrier permeability
Y Cui, Y Wang, X Song, H Ning, Y Zhang, Y Teng… - Cell Reports, 2021 - cell.com
The low level of transcytosis is a unique feature of cerebrovascular endothelial cells (ECs),
ensuring restrictive blood-brain barrier (BBB) permeability. Major facilitator superfamily …
ensuring restrictive blood-brain barrier (BBB) permeability. Major facilitator superfamily …
Mechanisms of neuroinvasion and neuropathogenesis by pathologic flaviviruses
L de Vries, AT Harding - Viruses, 2023 - mdpi.com
Flaviviruses are present on every continent and cause significant morbidity and mortality. In
many instances, severe cases of infection with flaviviruses involve the invasion of and …
many instances, severe cases of infection with flaviviruses involve the invasion of and …
Physiological Responses of Methanosarcina barkeri under Ammonia Stress at the Molecular Level: The Unignorable Lipid Reprogramming
C Liu, X Zhang, C Chen, Y Yin, G Zhao… - … Science & Technology, 2023 - ACS Publications
Acetotrophic methanogens' dysfunction in anaerobic digestion under ammonia pressure has
been widely concerned. Lipids, the main cytomembrane structural biomolecules, normally …
been widely concerned. Lipids, the main cytomembrane structural biomolecules, normally …
Compartmentalized replication organelle of flavivirus at the ER and the factors involved
Y Ci, L Shi - Cellular and Molecular Life Sciences, 2021 - Springer
Flaviviruses are positive-sense single-stranded RNA viruses that pose a considerable threat
to human health. Flaviviruses replicate in compartmentalized replication organelles derived …
to human health. Flaviviruses replicate in compartmentalized replication organelles derived …
[HTML][HTML] Impact of maternal nutrition in viral infections during pregnancy
Other than being a physiological process, pregnancy is a condition characterized by major
adaptations of maternal endocrine and metabolic homeostasis that are necessary to …
adaptations of maternal endocrine and metabolic homeostasis that are necessary to …
Host molecules regulating neural invasion of Zika virus and drug repurposing strategy
LY Tan, TV Komarasamy, W James… - Frontiers in …, 2022 - frontiersin.org
Zika virus (ZIKV) is a mosquito-borne, single-stranded RNA virus belonging to the genus
Flavivirus. Although ZIKV infection is usually known to exhibit mild clinical symptoms …
Flavivirus. Although ZIKV infection is usually known to exhibit mild clinical symptoms …