Primary cilia, antenna-like sensory organelles protruding from the surface of most vertebrate
cell types, are essential for regulating signalling pathways during development and adult …

Cilia are ubiquitous microtubule-based eukaryotic organelles that project from the cell to
generate motility or function in cellular signaling. Motile cilia or flagella contain axonemal …

Primary cilia are solitary, immotile sensory organelles present on most cells in the body that
participate broadly in human health, physiology and disease. Cilia generate a unique …

Dyneins make up a family of AAA+ motors that move toward the minus end of microtubules.
Cytoplasmic dynein is responsible for transporting intracellular cargos in interphase cells …

Intraflagellar transport (IFT) is the highly conserved process by which proteins are
transported along ciliary microtubules by a train-like polymeric assembly of IFT-A and IFT-B …

Intraflagellar transport (IFT) is a conserved process of cargo transport in cilia that is essential
for development and homeostasis in organisms ranging from algae to vertebrates. In …

Intraflagellar transport (IFT) is a highly conserved mechanism for motor-driven transport of
cargo within cilia, but how this cargo is selectively transported to cilia is unclear …

The assembly and maintenance of most cilia and eukaryotic flagella depends on
intraflagellar transport (IFT), the bidirectional movement of multi-megadalton IFT trains along …

Primary cilia act as cell surface antennae, coordinating cellular responses to sensory inputs
and signalling molecules that regulate developmental and homeostatic pathways. Cilia are …

The IFT-B complex mediates ciliary anterograde protein trafficking and membrane protein
export together with the BBSome. Bardet-Biedl syndrome (BBS) is caused by mutations in …