Copper complexes as antitumor agents: In vitro and in vivo evidence
Copper is an essential element for most aerobic organisms, with an important function as a
structural and catalytic cofactor, and in consequence, it is implicated in several biological …
structural and catalytic cofactor, and in consequence, it is implicated in several biological …
New Palladium (II) complexes with ONO chelated hydrazone ligand: Synthesis, characterization, DNA/BSA interaction, antioxidant and cytotoxicity
G Ayyannan, M Mohanraj, M Gopiraman… - Inorganica Chimica …, 2020 - Elsevier
There is a continuous finding of suitable metal complexes for biomedical and biological
applications since the discovery of cisplatin. Two biologically active complexes (2 and 3) are …
applications since the discovery of cisplatin. Two biologically active complexes (2 and 3) are …
Synthesis, characterization, design, molecular docking, anti COVID-19 activity, DFT calculations of novel Schiff base with some transition metal complexes
OA El-Gammal, AA El-Bindary, FS Mohamed… - Journal of Molecular …, 2022 - Elsevier
The elemental analyses, infrared, magnetic measures, UV–Visible, 1 H NMR, 13 C NMR,
and XRD analysis were used to study Co (II), Ni (II), and Cu (II) metal complexes (1–3) with a …
and XRD analysis were used to study Co (II), Ni (II), and Cu (II) metal complexes (1–3) with a …
Anticancer activity of a new copper (ii) complex with a hydrazone ligand. Structural and spectroscopic characterization, computational simulations and cell mechanistic …
We report here the synthesis, crystal structure, characterization and anticancer activity of a
copper (II)-hydrazone complex,[Cu (MeBHoVa)(H2O) 2](NO3)(for short, CuHL), against …
copper (II)-hydrazone complex,[Cu (MeBHoVa)(H2O) 2](NO3)(for short, CuHL), against …
[HTML][HTML] Antiproliferative activity of two copper (II) complexes on colorectal cancer cell models: Impact on ROS production, apoptosis induction and NF-κB inhibition
The main goal of this work was to screen the antiproliferative activity and mechanism of
actions of two copper complexes:[Cu (dmp) 2 (CH 3 CN)] 2+(1) and [Cu (phen) 2 (CH 3 CN)] …
actions of two copper complexes:[Cu (dmp) 2 (CH 3 CN)] 2+(1) and [Cu (phen) 2 (CH 3 CN)] …
Coordinating behavior of hydrazone ligand bearing chromone moiety towards Cu (II) ions: Synthesis, spectral, density functional theory (DFT) calculations, antitumor …
EM Abdelrhman, BA El‐Shetary… - Applied …, 2021 - Wiley Online Library
A new hydrazone ligand (FCSH; HL) was successfully synthesized by the reaction of
salicylaldehyde hydrazone with 3‐formylchromone. Seven copper (II) hydrazone complexes …
salicylaldehyde hydrazone with 3‐formylchromone. Seven copper (II) hydrazone complexes …
New Cu (II), Co (III) and Ni (II) metal complexes based on ONO donor tridentate hydrazone: Synthesis, structural characterization, and investigation of some biological …
Abstract New Cu (II), Co (III) and Ni (II) metal complexes of N'-(3-ethoxy-2-
hydroxybenzylidene) acetohydrazide (ehbahH 2) ligand derived from 3 …
hydroxybenzylidene) acetohydrazide (ehbahH 2) ligand derived from 3 …
Synthesis and characterization for pharmaceutical models from Co (II), Ni (II) and Cu (II)-thiophene complexes; apoptosis, various theoretical studies and …
HM Abumelha, F Alkhatib, S Alzahrani… - Journal of Molecular …, 2021 - Elsevier
Abstract New Co (II), Ni (II) and Cu (II) complexes were prepared from thiophene derivative
and then characterized to elucidate their chemical formulae. IR-spectral data suggested a …
and then characterized to elucidate their chemical formulae. IR-spectral data suggested a …
Promising Dual Anticancer and Antimetastatic Action by a Cu (II) Complex Derived from Acylhydrazone on Human Osteosarcoma Models
L Santa Maria de la Parra, AIB Romo… - Inorganic …, 2024 - ACS Publications
Osteosarcoma cancers are becoming more common in children and young adults, and
existing treatments have low efficacy and a very high mortality rate, making it pressing to …
existing treatments have low efficacy and a very high mortality rate, making it pressing to …
Ligational behavior of a new bis (bidentate NO) donor hydrazone towards Co (II), Ni (II), and Cu (II) ions: Preparation, spectral, thermal, biological, docking, and …
Reaction of 4, 6‐bis (1‐hydrazonoethyl) benzene‐1, 3‐diol with 3‐nitrobenzaldehyde gave
the new bis (bidentate) hydrazone ligand; 4, 6‐bis (3‐nitrobenzalen‐1‐yl) methylene) …
the new bis (bidentate) hydrazone ligand; 4, 6‐bis (3‐nitrobenzalen‐1‐yl) methylene) …