Recent update on the heterogeneity of the Alzheimer's disease spectrum
KA Jellinger - Journal of Neural Transmission, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia worldwide, is a mixed
proteinopathy (β-amyloid, tau and other proteins). Classically defined as a …
proteinopathy (β-amyloid, tau and other proteins). Classically defined as a …
Ethical issues when using digital biomarkers and artificial intelligence for the early detection of dementia
Dementia poses a growing challenge for health services but remains stigmatized and under‐
recognized. Digital technologies to aid the earlier detection of dementia are approaching …
recognized. Digital technologies to aid the earlier detection of dementia are approaching …
Caution,“normal” BMI: health risks associated with potentially masked individual underweight—EPMA Position Paper 2021
An increasing interest in a healthy lifestyle raises questions about optimal body weight.
Evidently, it should be clearly discriminated between the standardised “normal” body weight …
Evidently, it should be clearly discriminated between the standardised “normal” body weight …
The immune system as a therapeutic target for Alzheimer's disease
T Zieneldien, J Kim, D Sawmiller, C Cao - Life, 2022 - mdpi.com
Alzheimer's disease (AD) is a heterogeneous neurodegenerative disorder and is the most
common cause of dementia. Furthermore, aging is considered the most critical risk factor for …
common cause of dementia. Furthermore, aging is considered the most critical risk factor for …
The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022
DP Veitch, MW Weiner, M Miller, PS Aisen… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to improve
Alzheimer's disease (AD) clinical trials. Since 2006, ADNI has shared clinical, neuroimaging …
Alzheimer's disease (AD) clinical trials. Since 2006, ADNI has shared clinical, neuroimaging …
ADataViewer: exploring semantically harmonized Alzheimer's disease cohort datasets
Y Salimi, D Domingo-Fernández… - Alzheimer's Research & …, 2022 - Springer
Abstract Background Currently, Alzheimer's disease (AD) cohort datasets are difficult to find
and lack across-cohort interoperability, and the actual content of publicly available datasets …
and lack across-cohort interoperability, and the actual content of publicly available datasets …
Data and sample sharing as an enabler for large-scale biomarker research and development: the EPND perspective
N Bose, AJ Brookes, P Scordis, PJ Visser - Frontiers in Neurology, 2022 - frontiersin.org
Biomarker discovery, development, and validation are reliant on large-scale analyses of
high-quality samples and data. Currently, significant quantities of data and samples have …
high-quality samples and data. Currently, significant quantities of data and samples have …
[HTML][HTML] Transferability of Alzheimer's disease progression subtypes to an independent population cohort
In the past, methods to subtype or biotype patients using brain imaging data have been
developed. However, it is unclear whether and how these trained machine learning models …
developed. However, it is unclear whether and how these trained machine learning models …
Characteristics of amnestic patients with hypometabolism patterns suggestive of Lewy body pathology
A clinical diagnosis of Alzheimer's disease dementia (ADD) encompasses considerable
pathological and clinical heterogeneity. While Alzheimer's disease patients typically show a …
pathological and clinical heterogeneity. While Alzheimer's disease patients typically show a …
Semantic harmonization of Alzheimer's disease datasets using AD-Mapper
Background: Despite numerous past endeavors for the semantic harmonization of
Alzheimer's disease (AD) cohort studies, an automatic tool has yet to be developed …
Alzheimer's disease (AD) cohort studies, an automatic tool has yet to be developed …