Though a multi-facetted disorder, Parkinson's disease is prototypically characterized by
neurodegeneration of nigrostriatal dopaminergic neurons of the substantia nigra pars …

Diagnosis of Parkinson's disease (PD) relies on clinical history and physical examination,
but misdiagnosis is common in early stages. Identification of biomarkers for PD may allow …

Significantly enhanced catalytic activity of a nanocomposite composed of conducting
polymer poly (3, 4-ethylenedioxythiophene)(PEDOT) doped with graphene oxide (GO) was …

Parkinsonism and attention deficit hyperactivity disorder (ADHD) are widespread brain
disorders that involve disturbances of dopaminergic signaling. The sodium-coupled …

There is consensus that amelioration of the motor symptoms of Parkinson's disease is most
effective with l-DOPA (levodopa). However, this necessary therapeutic step is biased by an …

A novel tyrosinase-based biosensor was developed for the detection of dopamine (DA). For
increased selectivity, gold electrodes were previously modified with cobalt (II)-porphyrin …

Despite the different animal models of Parkinson's disease developed during the last years,
they still present limitations modelling the slow and progressive process of …

Increase in dopamine (DA) turnover was found to occur early in symptomatic Parkinson's
disease (PD) and to be functionally related to the dopamine transporter (DAT). The …

The blood-brain barrier supplies brain tissues with nutrients and filters certain compounds
from the brain back to the bloodstream. In several neurodegenerative diseases, including …

In neurotransmission process, dopamine (DA) is the key molecule. Hence, the detection of
dopamine plays a vital role in the primary diagnosis of diseases which is related to the …