The visual system of zebrafish and its use to model human ocular diseases
Free swimming zebrafish larvae depend mainly on their sense of vision to evade predation
and to catch prey. Hence, there is strong selective pressure on the fast maturation of visual …
and to catch prey. Hence, there is strong selective pressure on the fast maturation of visual …
Toward a better understanding of human eye disease: Insights from the zebrafish, Danio rerio
J Bibliowicz, RK Tittle, JM Gross - Progress in molecular biology and …, 2011 - Elsevier
Visual impairment and blindness is widespread across the human population, and the
development of therapies for ocular pathologies is of high priority. The zebrafish represents …
development of therapies for ocular pathologies is of high priority. The zebrafish represents …
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
DG Holland, A Burleigh, A Git… - EMBO molecular …, 2011 - embopress.org
The telomeric amplicon at 8p12 is common in oestrogen receptor‐positive (ER+) breast
cancers. Array‐CGH and expression analyses of 1172 primary breast tumours revealed that …
cancers. Array‐CGH and expression analyses of 1172 primary breast tumours revealed that …
Genes and pathways in optic fissure closure
A Patel, JC Sowden - Seminars in Cell & Developmental Biology, 2019 - Elsevier
Embryonic development of the vertebrate eye begins with the formation of an optic vesicle
which folds inwards to form a double-layered optic cup with a fissure on the ventral surface …
which folds inwards to form a double-layered optic cup with a fissure on the ventral surface …
An update on the genetics of ocular coloboma
Ocular coloboma is an uncommon, but often severe, sight-threatening condition that can be
identified from birth. This congenital anomaly is thought to be caused by maldevelopment of …
identified from birth. This congenital anomaly is thought to be caused by maldevelopment of …
iSyTE: integrated Systems Tool for Eye gene discovery
Purpose.: To facilitate the identification of genes associated with cataract and other ocular
defects, the authors developed and validated a computational tool termed iSyTE (i ntegrated …
defects, the authors developed and validated a computational tool termed iSyTE (i ntegrated …
Zeppo1 is a novel metastasis promoter that represses E-cadherin expression and regulates p120-catenin isoform expression and localization
Amplification of 8p11-12 in human breast cancers is associated with increased proliferation
and tumor grade and reduced metastasis-free patient survival. We identified Zeppo1 (zinc …
and tumor grade and reduced metastasis-free patient survival. We identified Zeppo1 (zinc …
Acute and sub-chronic toxicity of four cytostatic drugs in zebrafish
R Kovács, K Bakos, B Urbányi, J Kövesi… - … Science and Pollution …, 2016 - Springer
The acute and sub-chronic effects of four cytostatic drugs—5-fluorouracil (5-FU), cisplatin
(CisPt), etoposide (ET) and imatinib mesylate (IM)—on zebrafish (Danio rerio) were …
(CisPt), etoposide (ET) and imatinib mesylate (IM)—on zebrafish (Danio rerio) were …
Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme
Retinoic acid receptor (RAR) signaling is required for morphogenesis of the ventral optic cup
and closure of the choroid fissure, but the mechanisms by which this pathway regulates …
and closure of the choroid fissure, but the mechanisms by which this pathway regulates …
Schroedinger eigenmaps for the analysis of biomedical data
W Czaja, M Ehler - IEEE Transactions on Pattern Analysis and …, 2012 - ieeexplore.ieee.org
We introduce Schroedinger Eigenmaps (SE), a new semi-supervised manifold learning and
recovery technique. This method is based on an implementation of graph Schroedinger …
recovery technique. This method is based on an implementation of graph Schroedinger …