Resistance afforded by the sickle-cell trait against severe malaria has led to high
frequencies of the sickle-cell mutation [HBB; c. 20T> A, p. Glu6Val; OMIM: 141900 (HBB-βS)] …

Sickle cell disease (SCD) is a complex genetic disorder associated with multiple clinical
manifestations, including increased susceptibility to bacterial and viral infections. This …

Plasmodium falciparum malaria causes morbidity and mortality in African children with sickle
cell anemia (SCA), but comparisons of host responses to P falciparum between children with …

Human beings are sometime expose to the same to predisposing factors of a given
infectious disease, but the outcome in terms of disease manifestation differs greatly. This …

Previous research demonstrates that ADHD is considered a risk factor for COVID-19. The
current study attempts to investigate the relationships between infection, mortality and …

The global epidemic of Sickle cell anemia (SCA) is causing thousands of children to die.
SCA, a genetic disorder affecting the hemoglobin-globin chain, affects millions of people …

Background Urban malaria has received insufficient attention in the literature. The
prevalence and clinical characteristics of Plasmodium falciparum infection amongst patients …

Background Due to increased travel from endemic countries, malaria occurs more frequently
in non-endemic regions. It is a challenge for diagnostic laboratories in non-endemic …

Abstract Background In Plasmodium falciparum infection, clinical conditions such as
anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub …

Background Sickle cell disease (SCD) remains prevalent because heterozygous carriers
(HbAS) are partially resistant to Plasmodium falciparum malaria. Sickle hemoglobin (HbS) …