Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy

F Galli, JV Aguilera, B Palermo, SN Markovic… - Journal of experimental …, 2020 - Springer
Tumor-infiltrating immune cells play a key role against cancer. However, malignant cells are
able to evade the immune response and establish a very complex balance in which different …

Tailoring nanomaterials for targeting tumor‐associated macrophages

M Ovais, M Guo, C Chen - Advanced materials, 2019 - Wiley Online Library
Advances in the field of nanotechnology together with an increase understanding of tumor
immunology have paved the way for the development of more personalized cancer immuno …

Polymeric nanoparticles: the future of nanomedicine

BL Banik, P Fattahi, JL Brown - Wiley Interdisciplinary Reviews …, 2016 - Wiley Online Library
Polymeric nanoparticles (NP s) are one of the most studied organic strategies for
nanomedicine. Intense interest lies in the potential of polymeric NP s to revolutionize …

Noninvasive imaging of nanomedicines and nanotheranostics: principles, progress, and prospects

S Kunjachan, J Ehling, G Storm, F Kiessling… - Chemical …, 2015 - ACS Publications
Nanomedicine is defined as “the application of nanotechnology to medicine, including the
use of nanometer-sized carrier materials for facilitating disease diagnosis, disease treatment …

Imaging macrophages with nanoparticles

R Weissleder, M Nahrendorf, MJ Pittet - Nature materials, 2014 - nature.com
Nanomaterials have much to offer, not only in deciphering innate immune cell biology and
tracking cells, but also in advancing personalized clinical care by providing diagnostic and …

[HTML][HTML] Cell or cell membrane-based drug delivery systems

S Tan, T Wu, D Zhang, Z Zhang - Theranostics, 2015 - ncbi.nlm.nih.gov
Natural cells have been explored as drug carriers for a long period. They have received
growing interest as a promising drug delivery system (DDS) until recently along with the …

PET imaging with 89Zr: from radiochemistry to the clinic

MA Deri, BM Zeglis, LC Francesconi… - Nuclear medicine and …, 2013 - Elsevier
The advent of antibody-based cancer therapeutics has led to the concomitant rise in the
development of companion diagnostics for these therapies, particularly nuclear imaging …

Nanoparticles in practice for molecular-imaging applications: an overview

P Padmanabhan, A Kumar, S Kumar, RK Chaudhary… - Acta biomaterialia, 2016 - Elsevier
Nanoparticles (NPs) are playing a progressively more significant role in multimodal and
multifunctional molecular imaging. The agents like Superparamagnetic iron oxide (SPIO) …

Anti‐tumour strategies aiming to target tumour‐associated macrophages

X Tang, C Mo, Y Wang, D Wei, H Xiao - Immunology, 2013 - Wiley Online Library
Tumour‐associated macrophages (TAM s) represent a predominant population of
inflammatory cells that present in solid tumours. TAM s are mostly characterized as …

Near-infrared fluorescence imaging in immunotherapy

Y Ji, C Jones, Y Baek, GK Park, S Kashiwagi… - Advanced drug delivery …, 2020 - Elsevier
Near-infrared (NIR) light possesses many suitable optophysical properties for medical
imaging including low autofluorescence, deep tissue penetration, and minimal light …