Probing structure and function of ion channels using limited proteolysis and microfluidics

P Tompa - Chemical Society Reviews, 2016 - pubs.rsc.org

Signal transduction is the primary process by which cells respond to changes in their
physical and chemical environments. Cellular response is initiated through a signaling …

被引用次数：65 相关文章所有 7 个版本

[PDF] science.org Full View

Rational antibody design for undruggable targets using kinetically controlled biomolecular probes

CL Trkulja, O Jungholm, M Davidson, K Jardemark… - Science …, 2021 - science.org

Several important drug targets, eg, ion channels and G protein–coupled receptors, are
extremely difficult to approach with current antibody technologies. To address these targets …

被引用次数：10 相关文章所有 5 个版本

[PDF] usask.ca

[PDF][PDF] Production of fuels and chemicals from biomass-derived oil and lard

AO Adebanjo - 2005 - harvest.usask.ca

The concept of a 'valued ecosystem component'(VEC) was introduced in Canada in the
early 1980s to bring focus to project-specific environmental assessment (EA), and its …

被引用次数：9 相关文章所有 6 个版本

[PDF] usask.ca

[PDF][PDF] Exploring the ability of a distributed hydrological land surface model in simulating hydrological processes in the boreal forest environment

M Moges - 2015 - harvest.usask.ca

Land surface models (LSMs) simulate vertical fluxes, including evapotranspiration, in a
rigorous manner, and are included in atmospheric models, including Regional and Global …

被引用次数：5 相关文章

Multi-protease method

O Orwar, C Trkulja, M Davidson… - US Patent 11,408,883, 2022 - Google Patents

The present invention relates to methods of identifying an epitope on a protein that can be
bound by an antibody. Methods of the invention typically involve a step of limited or …

被引用次数：1 相关文章所有 4 个版本

[HTML] europepmc.org

Identifying TRP Channel Subunit Stoichiometry Using Combined Single Channel Single Molecule Determinations (SC-SMD)

LG Ceballos, A Asanov, L Vaca - Calcium Entry Channels in Non …, 2017 - taylorfrancis.com

The assembly of transient receptor potential (TRP) proteins into multimers and the existence
of heteromeric TRP pores of defined subunit composition were recognized early on in TRP …

被引用次数：1 相关文章所有 7 个版本

[PDF] googleapis.com

Methods for epitope selection

O Orwar, C Trkulja - US Patent 11,161,901, 2021 - Google Patents

The present invention relates to certain new methods to select epitopes for antibodies. The
present invention also provides a method of generating an antibody (eg a functional …

被引用次数：1 相关文章所有 4 个版本