Brain–gut axis after stroke

AK Arya, B Hu - Brain circulation, 2018 - journals.lww.com
Stroke leads to inflammatory and immune response in the brain and immune organs. The
gut or gastrointestinal tract is a major immune organ equipped with the largest pool of …

Disorders of consciousness in hospitalized patients with COVID-19: the role of the systemic inflammatory response syndrome

AK Boehme, K Doyle, KT Thakur, D Roh, S Park… - Neurocritical care, 2022 - Springer
Background Prevalence and etiology of unconsciousness are uncertain in hospitalized
patients with coronavirus disease 2019 (COVID-19). We tested the hypothesis that …

Acute splenic responses in patients with ischemic stroke and intracerebral hemorrhage

FS Vahidy, KN Parsha, MH Rahbar… - Journal of Cerebral …, 2016 - journals.sagepub.com
Animal models provide evidence of spleen mediated post-stroke activation of the peripheral
immune system. Translation of these findings to stroke patients requires estimation of pre …

Effects of β-adrenergic blockade on metabolic and inflammatory responses in a rat model of ischemic stroke

SY Lin, YY Wang, CY Chang, CC Wu, WY Chen… - Cells, 2020 - mdpi.com
Ischemic stroke provokes an inflammatory response concurrent with both sympathetic
nervous system activation and hyperglycemia. Currently, their crosstalk and consequences …

Infection, inflammation, and poststroke cognitive impairment

E Milosevich, N Demeyere… - Journal of the American …, 2024 - Am Heart Assoc
Background Infection and inflammation are dementia risk factors in population‐based
cohorts; however, studies in stroke are scarce. We determined the prevalence of infection …

Systemic inflammatory response syndrome and outcomes in intracerebral hemorrhage

AK Boehme, AN Hays, KP Kicielinski, K Arora… - Neurocritical care, 2016 - Springer
Background To identify the patients at greatest odds for systemic inflammatory response
syndrome (SIRS) and examine the association between SIRS and outcomes in patients …

Association between splenic contraction and the systemic inflammatory response after acute ischemic stroke varies with age and race

A Zha, F Vahidy, J Randhawa, K Parsha, T Bui… - Translational stroke …, 2018 - Springer
Animal models have demonstrated the deleterious contribution of splenic immunocytes on
secondary brain injury after stroke. While previous work has demonstrated splenic …

Back to basics: adherence with guidelines for glucose and temperature control in an American comprehensive stroke center sample

AW Alexandrov, P Palazzo, S Biby… - Journal of …, 2018 - journals.lww.com
Background: Variance from guideline-directed care for glucose and temperature control
remains unknown in the United States at a time when priorities have shifted to ensure rapid …

High serum levels of caspase-cleaved cytokeratin-18 are associated with malignant middle cerebral artery infarction patient mortality

L Lorente, MM Martín, A Pérez-Cejas, L Ramos… - BMC neurology, 2018 - Springer
Background There have been found apoptotic changes in brain tissue samples from
humans after cerebral ischemia. Caspase-cleaved cytokeratin (CCCK)-18 could appears in …

Impact of systemic inflammatory response syndrome on acute ischemic stroke patients treated with mechanical thrombectomy

M Jafari, K Katlowitz, C De la Garza, A Sellers… - Journal of the …, 2021 - Elsevier
Aim Systemic inflammatory response syndrome (SIRS) has been associated with poor
outcomes after acute ischemic stroke (AIS). The primary goal of this study was to determine …