The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through November 2012, and other …

Calcific aortic valve disease (CAVD) is the most common disorder affecting heart valves and
is characterized by thickening, fibrosis and mineralization of the aortic valve leaflets …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

Aortic stenosis is a common, potentially fatal condition that is set to become an increasing
public health burden. Once symptoms develop, there is an inexorable deterioration with a …

Calcific aortic valve disease (CAVD) encompasses the range of disease from initial
alterations in the cell biology of the leaflets to end-stage calcification resulting in left …

Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the
BAV can be found in isolation, it is often associated with other congenital cardiac lesions …

The recommendations listed in this document are, whenever possible, evidence-based.
Unlike other ACC/AHA practice guidelines, there is not a large body of peer-reviewed …

Background Hyperlipidemia has been suggested as a risk factor for stenosis of the aortic
valve, but lipid-lowering studies have had conflicting results. Methods We conducted a …

Background—Aortic stenosis (AS) is an active process with similarities to atherosclerosis.
The objective of this study was to assess the effect of cholesterol lowering with rosuvastatin …

with the matrix and with the periodicity of negative charges on collagen. Crystals initially
form octacalcium phosphate [Ca8H2 (PO4) 6· 5H2O], which reorganizes and seeds epitaxial …