The differential roles of T cells in non-alcoholic fatty liver disease and obesity

MA Van Herck, J Weyler, WJ Kwanten… - Frontiers in …, 2019 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) constitutes a spectrum of disease states
characterized by hepatic steatosis and is closely associated to obesity and the metabolic …

Emerging roles of T cells in the pathogenesis of nonalcoholic steatohepatitis and hepatocellular carcinoma

P Hirsova, AO Bamidele, H Wang, D Povero… - Frontiers in …, 2021 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver
disease worldwide. A significant proportion of patients with NAFLD develop a progressive …

Progressive liver fibrosis in non-alcoholic fatty liver disease

D Ramai, A Facciorusso, E Vigandt, B Schaf… - Cells, 2021 - mdpi.com
Non-alcoholic steatohepatitis (NASH) is a chronic and progressive form of non-alcoholic
fatty liver disease. Its global incidence is increasing and makes NASH an epidemic and a …

Insights from antiviral therapy into immune responses to hepatitis B and C virus infection

B Rehermann, R Thimme - Gastroenterology, 2019 - Elsevier
There are 257 million persons worldwide with chronic hepatitis B virus (HBV) infection, a
leading causes of liver cancer. Almost all adults with acute HBV infection have a rapid …

[HTML][HTML] Innate immunity and nonalcoholic fatty liver disease

J Kountouras, E Kazakos, F Kyrailidi… - Annals of …, 2023 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD), recently renamed as metabolic (dysfunction)-
associated fatty liver disease (MAFLD), is a complex, multifactorial disease that progresses …

Fine needle aspirates comprehensively sample intrahepatic immunity

US Gill, LJ Pallett, N Thomas, AR Burton, AA Patel… - Gut, 2019 - gut.bmj.com
Objective In order to refine new therapeutic strategies in the pipeline for HBV cure,
evaluation of virological and immunological changes compartmentalised at the site of …

[HTML][HTML] Incorporating mucosal-associated invariant T cells into the pathogenesis of chronic liver disease

AJ Czaja - World journal of gastroenterology, 2021 - ncbi.nlm.nih.gov
Mucosal-associated invariant T (MAIT) cells have been described in liver and non-liver
diseases, and they have been ascribed antimicrobial, immune regulatory, protective, and …

Sustained IFN-I stimulation impairs MAIT cell responses to bacteria by inducing IL-10 during chronic HIV-1 infection

X Tang, S Zhang, Q Peng, L Ling, H Shi, Y Liu… - Science …, 2020 - science.org
Mucosal-associated invariant T (MAIT) cells in HIV-1–infected individuals are functionally
impaired by poorly understood mechanisms. Single-cell transcriptional and surface protein …

Step by step: managing the complications of cirrhosis

I Perez, FJ Bolte, W Bigelow, Z Dickson… - Hepatic Medicine …, 2021 - Taylor & Francis
According to the Centers for Disease Control and Prevention, chronic liver disease and
cirrhosis is the 11th leading cause of death in the United States. Common causes of chronic …

Innate immunity and early liver inflammation

J Yang Zhou - Frontiers in Immunology, 2023 - frontiersin.org
The innate system constitutes a first-line defence mechanism against pathogens. 80% of the
blood supply entering the human liver arrives from the splanchnic circulation through the …