Endocrine function and neurobiology of the longest-living rodent, the naked mole-rat

YH Edrey, TJ Park, H Kang, A Biney… - Experimental …, 2011 - Elsevier
Animals that have evolved exceptional capabilities, such as extraordinary longevity may
reveal pertinent and potentially critical insights into biomedical research that are not readily …

EGF receptor expression, regulation, and function in breast cancer

SA Chrysogelos, RB Dickson - Breast cancer research and treatment, 1994 - Springer
Epidermal growth factor receptor (EGFR) overexpression correlates with both loss of
estrogen receptor (ER) and poor prognosis in breast cancer. Interestingly, in normal breast …

Structure and function of the type 3 deiodinase gene

A Hernandez - Thyroid, 2005 - liebertpub.com
Thyroid hormones (TH) are essential for normal growth and development in vertebrates, and
are important for the maintenance of normal metabolic activity in most tissues of the body …

Complex post-transcriptional regulation of EGF-receptor expression by EGF and TGF-α in human prostate cancer cells

D Seth, K Shaw, J Jazayeri, PJ Leedman - British journal of cancer, 1999 - nature.com
The epidermal growth factor receptor (EGFR) plays an important role in the development
and progression of prostate cancer and its overexpression is associated with decreased …

Identification of a novel AU-Rich element in the 3′ untranslated region of epidermal growth factor receptor mRNA that is the target for regulated RNA-binding proteins

LA Balmer, DJ Beveridge, JA Jazayeri… - … and Cellular Biology, 2001 - Taylor & Francis
The epidermal growth factor receptor (EGF-R) plays an important role in the growth and
progression of estrogen receptor-negative human breast cancers. EGF binds with high …

Localization of a negative thyroid hormone-response region in hepatic stearoyl-CoA desaturase gene 1

KM Waters, CW Miller, JM Ntambi - Biochemical and biophysical research …, 1997 - Elsevier
The effect of thyroid hormone on stearoyl-CoA desaturase gene 1 (SCD1) expression was
investigated in mouse liver. Daily injections of 15 μg triiodothyronine (T3)/100 g body weight …

Identification of functional positive and negative thyroid hormone-responsive elements in the rat apolipoprotein AI promoter

AH Taylor, P Wishart, DE Lawless, J Raymond… - Biochemistry, 1996 - ACS Publications
Transcription of the antiatherogenic protein apolipoprotein AI is regulated by the thyroid
hormone, l-triiodothyronine. Transient transfection and electrophoretic mobility shift assays …

Anti‐bombesin monoclonal antibodies modulate fetal mouse lung growth and maturation in utero and in organ cultures

ME Sunday, J Hua, B Reyes, H Masui… - The Anatomical …, 1993 - Wiley Online Library
Fetal pulmonary neuroendocrine cells (PNECs) contain abundant gastrin‐releasing peptide
(GRP, mammalian bombesin‐like peptide [BLP]). Previously, addition of bombesin resulted …

Mechanisms of EGF receptor regulation in breast cancer cells

SA Chrysogelos, RI Yarden, AH Lauber… - Breast cancer research …, 1994 - Springer
Overexpression of the EGF receptor in breast cancer correlates with poor prognosis and
failure on endocrine therapy for both ER−/EGFR+ and ER+/EGFR+ tumors, suggesting a …

Transforming growth factor-α in normal and neoplastic human endocrine tissues

DK Driman, MS Kobrin, JE Kudlow, SL Asa - Human pathology, 1992 - Elsevier
Transforming growth factor-α (TGF-α) is a polypeptide growth factor that binds to the
epidermal growth factor receptor and is thought to stimulate cell proliferation. It has been …