Kaposi's sarcoma and its associated herpesvirus

EA Mesri, E Cesarman, C Boshoff - Nature Reviews Cancer, 2010 - nature.com
Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals.
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

D Ganem - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
The linkage of Kaposi sarcoma (KS) to infection by a novel human herpesvirus (Kaposi
sarcoma–associated herpesvirus [KSHV]) is one of the great successes of contemporary …

[图书][B] HIV and the pathogenesis of AIDS.

JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone

KF Brulois, H Chang, ASY Lee, A Ensser… - Journal of …, 2012 - Am Soc Microbiol
Efficient genetic modification of herpesviruses such as Kaposi's sarcoma-associated
herpesvirus (KSHV) has come to rely on bacterial artificial chromosome (BAC) technology …

Viral latency and its regulation: lessons from the γ-herpesviruses

SH Speck, D Ganem - Cell host & microbe, 2010 - cell.com
Latency is a state of cryptic viral infection associated with genomic persistence and highly
restricted gene expression. Its hallmark is reversibility: under appropriate circumstances …

Kaposi sarcoma herpesvirus–induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma

HW Wang, MWB Trotter, D Lagos, D Bourboulia… - Nature …, 2004 - nature.com
The biology of Kaposi sarcoma is poorly understood because the dominant cell type in
Kaposi sarcoma lesions is not known,,,. We show by gene expression microarrays that …

[HTML][HTML] Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expression

J Vieira, PM O'Hearn - Virology, 2004 - Elsevier
A hallmark of all herpesvirus is the ability to exist in either a latent, or lytic, state of
replication, enabling the lifelong infection of its host. Kaposi's sarcoma (KS)-associated …

[HTML][HTML] Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis

A Grundhoff, D Ganem - The Journal of clinical investigation, 2004 - Am Soc Clin Investig
Kaposi sarcoma–associated (KS-associated) herpesvirus (KSHV) infection is linked to the
development of both KS and several lymphoproliferative diseases. In all cases, the resulting …

Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) epidemiology and pathogenesis

LA Dourmishev, AL Dourmishev… - Microbiology and …, 2003 - Am Soc Microbiol
Kaposi's sarcoma had been recognized as unique human cancer for a century before it
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …

KSHV infection and the pathogenesis of Kaposi's sarcoma

D Ganem - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Kaposi's sarcoma (KS) has long been suspected of having an infectious etiology on the
basis of its unusual epidemiology, histopathology, and natural history. Nearly a decade ago …