TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface

M Alves, P Asbell, M Dogru, G Giannaccare, A Grau… - The Ocular Surface, 2023 - Elsevier
Environmental risk factors that have an impact on the ocular surface were reviewed and
associations with age and sex, race/ethnicity, geographical area, seasonality, prevalence …

Corneal epithelial stem cells–physiology, pathophysiology and therapeutic options

Y Ruan, S Jiang, A Musayeva, N Pfeiffer, A Gericke - Cells, 2021 - mdpi.com
In the human cornea, regeneration of the epithelium is regulated by the stem cell reservoir of
the limbus, which is the marginal region of the cornea representing the anatomical and …

[HTML][HTML] Human conjunctiva organoids to study ocular surface homeostasis and disease

M Bannier-Hélaouët, J Korving, Z Ma, H Begthel… - Cell Stem Cell, 2024 - cell.com
The conjunctival epithelium covering the eye contains two main cell types: mucus-producing
goblet cells and water-secreting keratinocytes, which present mucins on their apical surface …

[HTML][HTML] Pharmacological treatment strategies of pterygium: drugs, biologics, and novel natural products

SS Baheran, RG Alany, S Schwikkard, W Muen… - Drug Discovery …, 2023 - Elsevier
Pterygium is a fibrovascular tissue growth invading the cornea. Adjunctive treatment post-
surgery includes conventional immunosuppressants as well as antiviral drugs. The use of …

5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional …

BWH Lee, AS Sidhu, IC Francis, MT Coroneo - The Ocular Surface, 2022 - Elsevier
Pterygium is an ultraviolet-related disease characterized by an aberrant, wing-shaped and
active wound-healing process. There is nothing quite as disheartening for the surgeon or …

Unravelling the molecular tapestry of pterygium: insights into genes for diagnostic and therapeutic innovations

M Gupta, S Arya, P Agrawal, H Gupta, R Sikka - Eye, 2024 - nature.com
Pterygium, an ocular surface disorder, manifests as a wing-shaped extension from the
corneoscleral limbus onto the cornea, impacting vision and causing inflammation. With a …

Evaluating the efficacy and safety of different pterygium surgeries: A review of the literature

M Palewski, A Budnik, J Konopińska - International journal of …, 2022 - mdpi.com
The search for the “gold standard” in the surgical treatment of pterygium has been ongoing
for over two decades. Despite the development of various surgical techniques, recurrence …

Randomness-restricted Diffusion Model for Ocular Surface Structure Segmentation

X Guo, H Wen, H Hao, Y Zhao, Y Meng… - … on Medical Imaging, 2024 - ieeexplore.ieee.org
Ocular surface diseases affect a significant portion of the population worldwide. Accurate
segmentation and quantification of different ocular surface structures are crucial for the …

Potential applications of artificial intelligence in image analysis in cornea diseases: a review

KY Tey, EZK Cheong, M Ang - Eye and Vision, 2024 - Springer
Artificial intelligence (AI) is an emerging field which could make an intelligent healthcare
model a reality and has been garnering traction in the field of medicine, with promising …

Therapeutic Potential and Mechanisms of Rosmarinic Acid and the Extracts of Lamiaceae Plants for the Treatment of Fibrosis of Various Organs

YC Boo - Antioxidants, 2024 - mdpi.com
Fibrosis, which causes structural hardening and functional degeneration in various organs,
is characterized by the excessive production and accumulation of connective tissue …