The future for blood‐stage vaccines against malaria
JS Richards, JG Beeson - Immunology and cell biology, 2009 - Wiley Online Library
Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …
Structural and immunological principles leading to chemically synthesized, multiantigenic, multistage, minimal subunit-based vaccine development
Dedicated to the memory of Professors Henry G. Kunkel and Bruce Merrifield (Rockefeller
University, New York), who introduced us to the fascinating worlds of immunology and …
University, New York), who introduced us to the fascinating worlds of immunology and …
Statistics for Biology and Health
M Gail, K Krickeberg, J Samet, A Tsiatis, W Wong - 2010 - Springer
Immunization is one of the great advances in public health. Figure 0.1 shows a camel with a
solar-powered refrigerator on his back carrying vaccines across a hot desert to the far …
solar-powered refrigerator on his back carrying vaccines across a hot desert to the far …
Efficacy of RTS, S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial
KA Bojang, PJM Milligan, M Pinder, L Vigneron… - The Lancet, 2001 - thelancet.com
Summary Background RTS, S/AS02 is a pre-erythrocytic malaria vaccine based on the
circumsporozoite surface protein of Plasmodium falciparum fused to HBsAg, incorporating a …
circumsporozoite surface protein of Plasmodium falciparum fused to HBsAg, incorporating a …
Randomised trial of efficacy of SPf66 vaccine against Plasmodium falciparum malaria in children in southern Tanzania
Effective, safe antimalarial vaccines have proved elusive. The synthetic polypeptide SPf66
vaccine is based on pre-erythrocytic and asexual blood-stage proteins of Plasmodium …
vaccine is based on pre-erythrocytic and asexual blood-stage proteins of Plasmodium …
Efficacy trial of malaria vaccine SPf66 in Gambian infants
SPf66 malaria vaccine is a synthetic protein with aminoacid sequences derived from pre-
erythrocytic and asexual blood-stage proteins of Plasmodium falciparum. SPf66 was found …
erythrocytic and asexual blood-stage proteins of Plasmodium falciparum. SPf66 was found …
Analysis of Multiple Plasmodium falciparum Infections in Tanzanian Children during the Phase III Trial of the Malaria Vaccine SPf66
HP Beck, I Felger, W Huber, S Steiger… - Journal of Infectious …, 1997 - academic.oup.com
In the first phase III efficacy trial of the malaria vaccine SPf66 in Africa, MOIs in SPf66-and
placebo-vaccinated children were analyzed by polymerase chain reaction-restriction …
placebo-vaccinated children were analyzed by polymerase chain reaction-restriction …
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red Blood Cells and Their Implications for Vaccine Design
LE Rodriguez, H Curtidor, M Urquiza… - Chemical …, 2008 - ACS Publications
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …
Vaccines for preventing malaria (SPf66)
PM Graves, H Gelband… - Cochrane Database …, 1996 - cochranelibrary.com
Background A malaria vaccine is badly needed. SPf66 was one of the earliest vaccines
developed. It is a synthetic peptide vaccine containing antigens from the blood stages of …
developed. It is a synthetic peptide vaccine containing antigens from the blood stages of …
Identification of Plasmodium falciparum MSP‐1 peptides able to bind to human red blood cells
M URQUIZA, LE RODRIGUEZ, JE SUAREZ… - Parasite …, 1996 - Wiley Online Library
To determine amino acid sequences of the Plasmodium falciparum MSP‐1 protein that
interact with red blood cell membranes in a specific receptor‐ligand interaction, 78 …
interact with red blood cell membranes in a specific receptor‐ligand interaction, 78 …