[HTML][HTML] Cross-talk between probiotic bacteria and the host immune system1

B Corthésy, HR Gaskins, A Mercenier - The Journal of nutrition, 2007 - Elsevier
Among the numerous purported health benefits attributed to probiotic bacteria, their capacity
to interact with the immune system of the host is now supported by an increasing number of …

Lactococci and lactobacilli as mucosal delivery vectors for therapeutic proteins and DNA vaccines

LG Bermúdez-Humarán, P Kharrat, JM Chatel… - Microbial cell …, 2011 - Springer
Abstract Food-grade Lactic Acid Bacteria (LAB) have been safely consumed for centuries by
humans in fermented foods. Thus, they are good candidates to develop novel oral vectors …

Protein secretion in Lactococcus lactis: an efficient way to increase the overall heterologous protein production

Y Le Loir, V Azevedo, SC Oliveira, DA Freitas… - Microbial Cell …, 2005 - Springer
Lactococcus lactis, the model lactic acid bacterium (LAB), is a food grade and well-
characterized Gram positive bacterium. It is a good candidate for heterologous protein …

[PDF][PDF] Heterologous protein production and delivery systems for Lactococcus lactis

S Nouaille, LA Ribeiro, A Miyoshi, D Pontes… - Genet Mol …, 2003 - researchgate.net
Lactic acid bacteria (LAB), widely used in the food industry, are present in the intestine of
most animals, including humans. The potential use of these bacteria as live vehicles for the …

Lactococcus lactis as a live vector: heterologous protein production and DNA delivery systems

DS Pontes, MSP De Azevedo, JM Chatel… - Protein expression and …, 2011 - Elsevier
Lactic acid bacteria (LAB), widely used in the food industry, are present in the intestine of
most animals, including humans. The potential use of these bacteria as mucosal delivery …

Production and Targeting of the Brucella abortus Antigen L7/L12 in Lactococcus lactis: a First Step towards Food-Grade Live Vaccines against Brucellosis

LA Ribeiro, V Azevedo, Y Le Loir… - Applied and …, 2002 - Am Soc Microbiol
Brucella abortus is a facultative intracellular gram-negative bacterial pathogen that infects
humans and animals by entry mainly through the digestive tract. B. abortus causes abortion …

An inducible surface presentation system improves cellular immunity against human papillomavirus type 16 E7 antigen in mice after nasal administration with …

LG Bermudez-Humaran… - Journal of medical …, 2004 - microbiologyresearch.org
Human papillomavirus type 16 (HPV-16) is the major causative agent of cervical cancer. To
date, vaccine strategies against HPV-16 are based on the ability of the E7 oncoprotein to …

Recent advances in genetic tools for engineering probiotic lactic acid bacteria

K Mugwanda, S Hamese, WF Van Zyl… - Bioscience …, 2023 - portlandpress.com
Synthetic biology has grown exponentially in the last few years, with a variety of biological
applications. One of the emerging applications of synthetic biology is to exploit the link …

Signal Peptide and Propeptide Optimization for Heterologous Protein Secretion in Lactococcus lactis

Y Le Loir, S Nouaille, J Commissaire… - Applied and …, 2001 - Am Soc Microbiol
Lactic acid bacteria are food-grade microorganisms that are potentially good candidates for
production of heterologous proteins of therapeutical or technological interest. We developed …

Optimization of the Lactococcus lactis nisin-controlled gene expression system NICE for industrial applications

I Mierau, K Olieman, J Mond, EJ Smid - Microbial Cell Factories, 2005 - Springer
Background The nisin-controlled gene expression system NICE of Lactococcus lactis is one
of the most widely used expression systems in Gram-positive bacteria. Despite its …