Onchocerciasis (river blindness)–more than a century of research and control

NW Brattig, RA Cheke, R Garms - Acta Tropica, 2021 - Elsevier
This review summarises more than a century of research on onchocerciasis, also known as
river blindness, and its control. River blindness is an infection caused by the tissue filaria …

Alternative treatment strategies to accelerate the elimination of onchocerciasis

M Boussinesq, G Fobi, AC Kuesel - International health, 2018 - academic.oup.com
The use of alternative (or complementary) treatment strategies (ATSs) ie differing from
annual community-directed treatment with ivermectin (CDTI) is required in some African foci …

The prevalence of onchocerciasis in Africa and Yemen, 2000–2018: a geospatial analysis

CA Schmidt, EA Cromwell, E Hill, KM Donkers… - BMC medicine, 2022 - Springer
Background Onchocerciasis is a disease caused by infection with Onchocerca volvulus,
which is transmitted to humans via the bite of several species of black fly, and is responsible …

Progress towards onchocerciasis elimination in the participating countries of the African Programme for Onchocerciasis Control: epidemiological evaluation results

AH Tekle, HGM Zouré, M Noma, M Boussinesq… - Infectious Diseases of …, 2016 - Springer
Abstract Background The African Programme for Onchocerciasis Control (APOC) was
created in 1995 to establish community-directed treatment with ivermectin (CDTi) in order to …

Model building and assessment of the impact of covariates for disease prevalence mapping in low-resource settings: to explain and to predict

E Giorgi, C Fronterrè, PM Macharia… - Journal of The …, 2021 - royalsocietypublishing.org
This paper provides statistical guidance on the development and application of model-
based geostatistical methods for disease prevalence mapping. We illustrate the different …

Reaching the last mile: main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa

G Gebrezgabiher, Z Mekonnen… - Infectious diseases of …, 2019 - mednexus.org
Background: Onchocerciasis (river blindness), caused by the filarial worm species
Onchocerca volvulus, is a serious vector-borne neglected tropical disease (NTD) of public …

[HTML][HTML] Research for new drugs for elimination of onchocerciasis in Africa

AC Kuesel - International Journal for Parasitology: Drugs and Drug …, 2016 - Elsevier
Onchocerciasis is a parasitic, vector borne disease caused by the filarial nematode
Onchocerca volvulus. More than 99% of the population at risk of infection live in Africa …

The burden of skin disease and eye disease due to onchocerciasis in countries formerly under the African Programme for Onchocerciasis Control mandate for 1990 …

NVS Vinkeles Melchers, WA Stolk… - PLoS Neglected …, 2021 - journals.plos.org
Background Onchocerciasis (“river blindness”) can cause severe morbidity, including vision
loss and various skin manifestations, and is targeted for elimination using ivermectin mass …

Onchocerciasis‐associated epilepsy: From recent epidemiological and clinical findings to policy implications

R Colebunders, AK Njamnshi, M van Oijen… - Epilepsia …, 2017 - Wiley Online Library
A high prevalence of epilepsy is reported in many onchocerciasis‐endemic regions. In this
paper we discuss recent epidemiological and clinical aspects as well as public health …

[HTML][HTML] Genome-based tools for onchocerciasis elimination: Utility of the mitochondrial genome for delineating Onchocerca volvulus transmission zones

KE Crawford, SM Hedtke, SR Doyle, AC Kuesel… - International Journal for …, 2024 - Elsevier
National programs in Africa have expanded their objectives from control of onchocerciasis
(river blindness) as a public health problem to elimination of parasite transmission …